Nuzzi Raffaele, Marolo Paola, Nuzzi Alessia
Eye Clinic Section, Department of Surgical Sciences, University of Turin, Turin, Italy.
Department of Clinical Sciences and Community Health, Eye Clinic San Giuseppe Hospital,IRCCS Multimedica, University of Milan, Milan, Italy.
J Ophthalmol. 2021 Apr 14;2021:5013529. doi: 10.1155/2021/5013529. eCollection 2021.
Glaucoma is a chronic silent disease and an irreversible cause of blindness worldwide. Research has made many efforts to improve disease control and especially to anticipate both early diagnosis and treatment of advanced stages of glaucoma. In terms of prevention, networking between professionals and nonprofessionals is an important goal to disseminate information and help diagnose the disease early. On the other hand, the most recent approaches to treat glaucoma outcomes in its advanced stages include electrical stimulation, stem cells, exosomes, extracellular vesicles, and growth factors. Finally, neuronal plasticity-based rehabilitation methods are being studied to reeducate patients in order to stimulate their residual visual capacity. This review provides an overview of new approaches to future possible glaucoma treatment modalities and gives insight into the perspectives available nowadays in this field.
青光眼是一种慢性隐匿性疾病，是全球不可逆性失明的一个原因。研究已做出诸多努力来改善疾病控制，尤其是提前对青光眼晚期进行早期诊断和治疗。在预防方面，专业人员与非专业人员之间建立联系是传播信息并帮助早期诊断该疾病的一个重要目标。另一方面，治疗青光眼晚期的最新方法包括电刺激、干细胞、外泌体、细胞外囊泡和生长因子。最后，基于神经可塑性的康复方法正在研究中，目的是对患者进行再教育，以刺激其残余视觉能力。本综述概述了未来可能的青光眼治疗方式的新方法，并深入探讨了该领域目前的观点。
