Department of Neurology and Clinical Neurophysiology, Albert Schweitzer Hospital, Dordrecht, the Netherlands.
Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, the Netherlands.
Cephalalgia. 2021 Sep;41(10):1124-1127. doi: 10.1177/03331024211006843. Epub 2021 May 2.
Paroxysmal localized hyperhidrosis is a rare disorder of the central autonomic nervous system. No association between paroxysmal hyperhidrosis and severe headache has been previously described in literature. A 65-year-old woman with idiopathic paroxysmal localized hyperhidrosis combined with severe holocranial headache attacks is described in this case report. Extensive diagnostic testing by means of laboratory examinations, 24-hour urinalyses, chest X-ray, abdominal ultrasound and computed tomography scans, and brain and spinal cord magnetic resonance imaging could not identify an underlying disorder. A diagnosis of idiopathic paroxysmal localized hyperhidrosis was made, and the patient was successfully treated with clonidine 0.075 mg three times a day, without any side effects.
Paroxysmal localized hyperhidrosis is a rare central autonomic nervous system disorder that can occur in combination with severe headache. Both the headache and paroxysmal hyperhidrosis complaints were treated effectively with clonidine in the patient described in this case-report.
阵发性局部多汗症是一种罕见的中枢自主神经系统疾病。之前的文献中没有描述过阵发性多汗症与严重头痛之间的关联。本文报告了一例 65 岁女性特发性阵发性局部多汗症伴严重全颅头痛发作的病例。通过实验室检查、24 小时尿液分析、胸部 X 线、腹部超声和计算机断层扫描以及脑和脊髓磁共振成像进行了广泛的诊断性检查，未能确定潜在疾病。诊断为特发性阵发性局部多汗症，患者每天服用 0.075 毫克可乐定三次，成功治疗，无任何副作用。
阵发性局部多汗症是一种罕见的中枢自主神经系统疾病，可与严重头痛同时发生。在本病例报告中，患者的头痛和阵发性多汗症均用可乐定有效治疗。
