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[关节病的充血性发作:是炎症爆发吗?]

[A congestive bout of arthrosis: is it an inflammatory outbreak?].

作者信息

Loyau G, Courtheoux F, Guaydier-Souquières G, Rousselot P

机构信息

CHU de Caen.

出版信息

Rev Rhum Mal Osteoartic. 1988 Apr 30;55(6):440-3.

PMID:3393839
Abstract

The arthrotic disease is frequently dotted with "bouts" characterized by a new outbreak of pain which may lead to inflammation and sometimes, for superficial joints, characterized by increased local heat and, mostly, hydarthrosis. But, the inflammatory component usually remains moderate and many clinicians prefer the term of congestive bout which, in addition, respects the classical opposition arthrosis-arthritis. Actually, this opposition is not so clear-cut, and it appears more and more clearly that arthrosis is a multi-factorial disease where, in addition to mechanical, genetic or metabolic factors, the synovial inflammation plays a major role in the degeneration of the cartilage. The findings of arthroscopy and pathology let to believe that congestive bouts are actually inflammatory bouts.

摘要

关节疾病常伴有“发作期”,其特征为疼痛再次发作,可能导致炎症,有时对于浅表关节,还表现为局部发热加剧,且大多伴有关节积液。但是,炎症成分通常保持中度,许多临床医生更喜欢使用“充血性发作”这一术语,此外,该术语也符合骨关节炎与关节炎的传统区分。实际上,这种区分并非如此清晰,越来越明显的是,骨关节炎是一种多因素疾病,除了机械、遗传或代谢因素外,滑膜炎症在软骨退变中起主要作用。关节镜检查和病理学结果让人相信,充血性发作实际上就是炎症发作。

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