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shave 切除术、电干燥术和刮除术联合咪喹莫特 5%乳膏治疗转移性黑素瘤的新方法。

Novel Treatment of In-Transit Metastatic Melanoma With Shave Excision, Electrodesiccation and Curettage, and Topical Imiquimod 5% Cream.

出版信息

J Drugs Dermatol. 2021 May 1;20(5):555-557. doi: 10.36849/JDD.5675.

DOI:10.36849/JDD.5675
PMID:33938702
Abstract

In-transit metastatic melanoma is classified as a regional intralymphatic metastasis of melanoma. Currently, there is no standardized regimen used to treat in-transit metastatic melanoma, and therapy is individualized based on the patient. While many patients undergo surgical procedures, those with surgical contraindications or declination face challenges when attempting to find adequate treatment options. This case report demonstrates the successful treatment of multiple in-transit metastatic melanoma lesions using the combination of shave excision, electrodesiccation and curettage, and topical imiquimod cream. Several months later, examination showed clinical resolution of the original metastatic lesions. This treatment regimen may provide an alternative option for a select group of patients with certain comorbidities and therapeutic contraindications. J Drugs Dermatol. 20(5):555-557. doi:10.36849/JDD.5675.

摘要

转移性黑色素瘤在转移过程中被归类为黑色素瘤的区域性淋巴管内转移。目前,尚无标准化的方案用于治疗转移性黑色素瘤在转移过程中,并且治疗是根据患者的情况个体化的。虽然许多患者接受了手术,但对于有手术禁忌症或拒绝手术的患者,在寻找足够的治疗选择时会面临挑战。本病例报告展示了使用刮除术、电干燥术和切除术联合咪喹莫特乳膏成功治疗多个转移性黑色素瘤在转移过程中的病变。几个月后,检查显示原发转移性病变的临床消退。对于某些合并症和治疗禁忌症的特定患者群体,这种治疗方案可能提供一种替代选择。J 皮肤病药物杂志。20(5):555-557.doi:10.36849/JDD.5675.

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Successful treatment of in-transit metastatic melanoma with combination intralesional T-VEC and topical imiquimod immunotherapy.联合瘤内 T-VEC 和外用咪喹莫特免疫疗法成功治疗转移性黑色素瘤。
J Immunother Cancer. 2024 Nov 19;12(11):e009581. doi: 10.1136/jitc-2024-009581.
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Imiquimod as Local Immunotherapy in the Management of Premalignant Cutaneous Conditions and Skin Cancer.
咪喹莫特作为局部免疫疗法在皮肤癌前病变和皮肤癌的治疗中的应用。
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