病例报告：曾感染登革热病毒的肾移植受者从死亡供者感染登革热病毒。
Case Report: Transmission of Dengue Virus from a Deceased Donor to a Kidney Transplant Recipient Previously Infected by Dengue Virus.
机构信息
1Centre Hospitalier Universitaire Félix Guyon, réanimation Polyvalente, Allée des Topazes, 97400, Saint Denis, France.
2Centre Hospitalier Universitaire Félix Guyon, Service de Microbiologie, Allée des Topazes, 97400, Saint Denis, France.
出版信息
Am J Trop Med Hyg. 2021 May 3;104(6):2199-2201. doi: 10.4269/ajtmh.21-0137.
Since 2018, a dengue epidemic has been ongoing in the French overseas department of Reunion Island, in the Indian Ocean, with more than 25,000 serologically confirmed cases. Currently, three dengue serotypes have been identified in Réunion Island (DENV-1, DENV-2, and DENV-3) progressing in the form of epidemic outbreaks. This arbovirus is mainly transmitted by mosquitoes of the genus Aedes and may be responsible for serious clinical forms. To date, very few cases of kidney transplant-related dengue virus infection have been described. Here we report the first case of severe dengue virus infection related to kidney transplantation from a patient previously infected with dengue. Testing for dengue fever with PCR search in donor's urine may help complete the pretransplant assessment in areas where this disease occurs.
自 2018 年以来，印度洋法属留尼汪海外省一直爆发登革热疫情，血清学确诊病例超过 25000 例。目前，在留尼汪岛已发现三种登革热血清型（DENV-1、DENV-2 和 DENV-3），它们以流行爆发的形式发展。这种虫媒病毒主要由伊蚊属的蚊子传播，可能导致严重的临床症状。迄今为止，与肾移植相关的登革热病毒感染病例非常少。在此，我们报告首例由先前感染过登革热的肾移植患者引起的严重登革热病毒感染病例。在发生这种疾病的地区，对供体尿液进行 PCR 搜索以检测登革热可能有助于完成移植前评估。
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