基孔肯雅热的黏膜皮肤表现：一家三级护理医院的经验。
Mucocutaneous manifestations of Chikungunya fever, an experience of tertiary care hospital.
机构信息
Department of Dermatology, Jinnah Postgraduate Medical Centre JPMC, Karachi, Pakistan.
出版信息
J Pak Med Assoc. 2021 Feb;71(2(B)):619-623. doi: 10.47391/JPMA.693.
OBJECTIVE
To determine the frequencies of mucocutaneous manifestations of chikungunya fever, and to determine the association of positive serology with manifestations.
METHODS
The observational cross-sectional study was conducted at the Department of Dermatology, Jinnah Postgraduate Medical Centre, Karachi, from May 15, 2018, to January 15, 2019, and comprised patients who presented with early and late manifestations of chikungunya fever. Different cutaneous manifestations were confirmed by a consultant dermatologist. Data was analysed using SPSS 23.
RESULTS
Of the 67 patients, 46(68.7%) were females and 21(31.3%) were males. The overall mean age was 30.24±7.89 years. Hyperpigmentation was the most frequent finding 31(46%), followed by maculopapular rashes and oral ulcers in 17(25%) each, and diffuse hair fall in 14(20%). There was no significant association between clinically suspected cases and serology-positive patients.
CONCLUSIONS
Chikungunya fever presented with unusual mucocutaneous findings, some of which remained present months or even years after the onset of chikungunya fever.
目的
确定基孔肯雅热的黏膜皮肤表现频率，并确定血清学阳性与表现之间的关联。
方法
本观察性横断面研究于 2018 年 5 月 15 日至 2019 年 1 月 15 日在卡拉奇的吉纳纳研究生医学中心皮肤科进行，纳入出现基孔肯雅热早期和晚期表现的患者。顾问皮肤科医生确认了不同的皮肤表现。使用 SPSS 23 对数据进行分析。
结果
在 67 例患者中，46 例（68.7%）为女性，21 例（31.3%）为男性。总体平均年龄为 30.24±7.89 岁。最常见的发现是色素沉着过度 31 例（46%），其次是斑丘疹和口腔溃疡各 17 例（25%），弥漫性脱发 14 例（20%）。临床上疑似病例与血清学阳性患者之间无显著关联。
结论
基孔肯雅热表现出不寻常的黏膜皮肤表现，其中一些在基孔肯雅热发作数月甚至数年后仍存在。
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