Department of Otolaryngology - Head & Neck Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, U.S.A.
Department of Otolaryngology - Head & Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, U.S.A.
Laryngoscope. 2021 Nov;131(11):2519-2522. doi: 10.1002/lary.29598. Epub 2021 May 4.
Stevens-Johnson syndrome (SJS) is a rare but severe mucocutaneous epidermolysis commonly triggered by medications. SJS is characterized by mucocutaneous lesions of the trunk, face, and limbs, as well as the oral cavity, gastrointestinal tract, and respiratory tract. Although uncommon, laryngeal involvement in SJS can lead to severe respiratory, phonatory and deglutitive complications. Providers caring for patients with SJS should maintain a high index of suspicion for laryngeal involvement and low threshold to solicit Otolaryngology consultation. Laryngeal complications can be more expediently managed when anticipated early in the course of disease. Laryngoscope, 131:2519-2522, 2021.
史蒂文斯-约翰逊综合征（SJS）是一种罕见但严重的黏膜-皮肤型表皮松解症，通常由药物引发。SJS 的特征是躯干、面部和四肢以及口腔、胃肠道和呼吸道的黏膜-皮肤损伤。虽然不常见，但 SJS 中的喉部受累可导致严重的呼吸、发声和吞咽并发症。治疗 SJS 患者的医护人员应高度警惕喉部受累，并降低耳鼻喉科会诊的门槛。当疾病早期出现时，喉部并发症可以更迅速地得到处理。《喉镜》，131：2519-2522，2021。
