Stinner G, Floersheim G L
Transplantation. 1977 Sep;24(3):218-22. doi: 10.1097/00007890-197709000-00007.
Isogenic bone marrow transplantation was performed in "nude" and normal C3H mice after lethal doses of dimethylmyleran (DMM), meso-DMM, and (+/-) DMM were given. Nude mice were not more sensitive to DMM or its isomers than normal mice. With adequate cell doses in the range of 3 X 10(6) to 30 X 10(6) bone marrow cells or 10 X 10(6) to 30 X 10(6) spleen cels, the survival rate after lethal chemotherapy was not significantly different between nude mice reconstituted with a graft from nude donors and normal mice reconstituted with a graft from normal donors. Only with suboptimal cell dose (1 X 10(6) bone marrow cells) was survival superior in normal mice. Thinsic factor. Nude mice accepted also bone marrow grafts from allogeneic nude donors.
在给予致死剂量的二甲磺酸丁酯（DMM）、内消旋 - DMM和（±） - DMM后，对“裸”鼠和正常C3H小鼠进行了同基因骨髓移植。裸鼠对DMM或其异构体的敏感性并不比正常小鼠更高。当骨髓细胞剂量在3×10⁶至30×10⁶个细胞范围内或脾细胞剂量在10×10⁶至30×10⁶个细胞范围内时，接受来自裸供体移植的裸鼠和接受来自正常供体移植的正常小鼠在致死性化疗后的存活率没有显著差异。只有在细胞剂量不足（1×10⁶个骨髓细胞）时，正常小鼠的存活率才更高。内在因素。裸鼠也接受来自同种异体裸供体的骨髓移植。
