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资源有限环境下儿童水疱性疾病(中毒性表皮坏死松解症)

Childhood vesiculobulous disorder (toxic epidermal necrolysis) in a resource constrained setting.

机构信息

abia state university,uturu,nigeria.

ABIA STATE UNIVERSITY TEACHING HOSPITAL ABA.

出版信息

Acta Biomed. 2021 Apr 30;92(S1):e2021085. doi: 10.23750/abm.v92iS1.8604.

DOI:10.23750/abm.v92iS1.8604
PMID:33944854
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8142752/
Abstract

We report a case of childhood vesiculobulous disorder of the severity of Toxic Epidermal Necrolysis(TEN) in a 4 year ten month old female child resulting from caregiver prescribed medication. She is one of 4 children of a non consanguineous marriage with no family history of similar adverse drug reactions. She was initially managed in a private hospital before referral to our centre where we observed constraints of funds and crisis of confidence on the part of the parents. The need for enlightenment and counseling of care givers on cause of illness and advocacy for special funds for adverse drug events especially for indigent patients is hereby highlighted. Also the importance of optimization of available health care resources even in the midst of poor circumstances is emphasized.

摘要

我们报告了一例儿童水疱病,严重程度为中毒性表皮坏死松解症(TEN),发生在一名 4 岁 10 个月大的女童身上,是由照顾者处方的药物引起的。她是非近亲结婚的 4 个孩子之一,没有家族中类似药物不良反应的病史。她最初在一家私立医院接受治疗,然后转至我们中心,我们观察到父母在资金和信心方面存在限制。因此,我们强调需要对照顾者进行有关疾病原因的启蒙和咨询,并倡导为药物不良反应,特别是为贫困患者提供特别资金。同时,即使在贫困环境下,也要强调优化现有卫生保健资源的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04e6/8142752/00ed21c2e268/ACTA-92-85-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04e6/8142752/00ed21c2e268/ACTA-92-85-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04e6/8142752/00ed21c2e268/ACTA-92-85-g001.jpg

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本文引用的文献

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8
Toxic epidermal necrolysis: an eruption resembling scalding of the skin.中毒性表皮坏死松解症:一种类似皮肤烫伤的皮疹。
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Treatment of severe drug reactions: Stevens-Johnson syndrome, toxic epidermal necrolysis and hypersensitivity syndrome.严重药物反应的治疗:史蒂文斯-约翰逊综合征、中毒性表皮坏死松解症和超敏反应综合征。
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Association of human herpesvirus 6 infection with drug reaction with eosinophilia and systemic symptoms.人类疱疹病毒6型感染与伴有嗜酸性粒细胞增多和全身症状的药物反应的关联。
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