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手术护理包对结直肠手术部位感染发生率的影响:一项准实验干预。

Effect of a Surgical Care Bundle on the Incidence of Surgical Site Infection in Colorectal Surgery: A Quasi-Experimental Intervention.

机构信息

Department of Surgery, Rey Juan Carlos Hospital, Móstoles, Madrid, Spain.

Department of Preventive Medicine, Alcorcón Foundation University Hospital, Alcorcón, Madrid; Department of Medical Specialties and Public Health, Rey Juan Carlos University, Alcorcón, Madrid; Spain.

出版信息

Rev Invest Clin. 2021 May 4;73(4):251-258. doi: 10.24875/RIC.21000067.

Abstract

BACKGROUND

Surgical site infections (SSI) have an important impact on morbidity and mortality.

OBJECTIVE

This study, therefore, sought to assess the effect of a surgical care bundle on the incidence of SSI in colorectal surgery.

METHODS

We conducted a quasi-experimental intervention study with reference to the introduction of a surgical care bundle in 2011. Our study population, made up of patients who underwent colorectal surgery, was divided into the following two periods: 2007-2011 (pre-intervention) and 2012-2017 (post-intervention). The intervention's effect on SSI incidence was analyzed using adjusted odds ratios (OR).

RESULTS

A total of 1,727 patients were included in the study. SSI incidence was 13.0% before versus 11.6% after implementation of the care bundle (OR: 0.88, 95% confidence interval: 0.66-1.17, p = 0.37). Multivariate analysis showed that cancer, chronic obstructive pulmonary disease, neutropenia, and emergency surgery were independently associated with SSI. In contrast, laparoscopic surgery proved to be a protective factor against SSI.

CONCLUSIONS

Care bundles have proven to be very important in reducing SSI incidence since the measures that constitute these protocols are mutually reinforcing. In our study, the implementation of a care bundle reduced SSI incidence from 13% to 11.6%, though the reduction was not statistically significant.

摘要

背景

手术部位感染(SSI)对发病率和死亡率有重要影响。

目的

因此,本研究旨在评估外科护理包对结直肠手术 SSI 发生率的影响。

方法

我们进行了一项准实验干预研究,参考 2011 年引入的外科护理包。我们的研究人群由接受结直肠手术的患者组成,分为以下两个时期:2007-2011 年(干预前)和 2012-2017 年(干预后)。使用调整后的优势比(OR)分析干预对 SSI 发生率的影响。

结果

共有 1727 名患者纳入研究。护理包实施前 SSI 发生率为 13.0%,实施后为 11.6%(OR:0.88,95%置信区间:0.66-1.17,p=0.37)。多变量分析显示,癌症、慢性阻塞性肺疾病、中性粒细胞减少症和急诊手术与 SSI 独立相关。相比之下,腹腔镜手术被证明是 SSI 的保护因素。

结论

护理包在降低 SSI 发生率方面非常重要,因为这些方案中的措施是相互加强的。在我们的研究中,护理包的实施将 SSI 发生率从 13%降低到 11.6%,尽管降低并不具有统计学意义。

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