Department of Anaesthesia and Intensive Care Medicine, Cork University Hospital and University College Cork, Ireland.
Department of Anatomy and Neuroscience, University College Cork, Ireland.
Med Ultrason. 2021 Nov 25;23(4):418-423. doi: 10.11152/mu-2979. Epub 2021 Apr 22.
Retrolaminar block (RB) is known to confer chest wall analgesia but, its mechanism has not been established. Our primary objective was to determine if the spread of injectate following RB extends to the paravertebral space (PVS). Second-ary objectives were to determine the predefined anatomical areas and nervous tissues contacted by injectate; the effect of volume on spread; and the extent to which experts can predict PVS spread based on examination of US videos of the injection.
US-guided RB was performed on cadavers using a single injection technique of 10, 20 or 30 ml dye. Anatomical dissection was performed to identify the extent of spread of injectate to the retrolaminar, intercostal and PVS. Ultrasound recordings of the injection were independently evaluated by experts in US-guided regional anaesthesia.
Spread of injectate to the ipsilateral PVS was identified in 6/10 dissected regions (0/1, 1/3 and 5/6 when injectate volumes of 10, 20 and 30ml were administered respectively). The extent of cephalad-caudad spread within the PVS varied from 1 to 3 levels. Expert interpretation of ultrasound images regarding spread to the PVS demonstrated poor correlation with dye staining observed on dissection.
Injectate spread following RB demonstrated substantial variability. Inconsistent spread to the ipsilateral PVS may account for clinically occurring incomplete blocks. The likelihood of spread to the ipsilateral PVS was greater when a larger volume was injected. Expert evaluation of the dynamic ultrasound images obtained at injection can-not reliably predict spread to the PVS.
经椎旁肌间隙阻滞(RB)可提供胸壁镇痛,但其作用机制尚未明确。本研究的主要目的是确定 RB 注射后,注射药物是否会扩散至椎旁间隙(PVS)。次要目的是确定注射药物接触的预设解剖区域和神经组织;确定容积对扩散的影响;以及专家根据注射超声视频检查来预测 PVS 扩散的程度。
对尸体进行超声引导下 RB,采用 10、20 或 30ml 染料的单次注射技术。解剖以确定注射药物向椎旁肌间隙、肋间和 PVS 的扩散范围。超声引导区域阻滞专家独立评估注射的超声记录。
在 6/10 个解剖区域中发现同侧 PVS 有注射药物扩散(当注射容积为 10、20 和 30ml 时,分别为 0/1、1/3 和 5/6)。PVS 内头侧-尾侧扩散范围从 1 个到 3 个节段不等。专家对超声图像关于向 PVS 扩散的解读与解剖时观察到的染料染色相关性较差。
RB 后注射药物的扩散具有很大的变异性。向同侧 PVS 的不一致扩散可能导致临床上不完全阻滞的发生。当注射更大容积时,向同侧 PVS 扩散的可能性更大。在注射时获得的动态超声图像的专家评估不能可靠地预测 PVS 的扩散。