Hôpitaux Universitaires de Strasbourg, Centre de Référence Maladies Rares Orales et Dentaires (O-Rares), Pôle de Médecine et de Chirurgie Bucco-Dentaires, Strasbourg, France.
Université de Strasbourg, Faculté de Chirurgie Dentaire, Strasbourg, France.
J Oral Implantol. 2022 Jun 1;48(3):251-260. doi: 10.1563/aaid-joi-D-20-00384.
Systemic sclerosis is a rare multisystem autoimmune disorder that significantly impacts the orofacial region. Several oral features including microstomia and increased tooth loss contribute to the mouth-related disability. Prosthetic rehabilitation is very challenging in these patients. As the spectrum of dental implants indications has been recently extended to patients with various systemic disorders, the aim of this systematic review was to evaluate the outcome of dental implants in patients with systemic sclerosis. A literature search was conducted in Medline/PubMed database to identify eligible case reports. Ten publications were included in qualitative synthesis. A total of 71 implants have been reported in 10 patients with systemic sclerosis with a mean of 7.1 ± 3.8 implants per patient. Preimplant surgeries have been described for 3 patients. Implant survival rates were higher than 98%, but the mean follow-up time was only 28.3 ± 18.6 months. Complications have been observed in 3 patients with 1 implant failure and peri-implant bone resorption in 2 patients. Although implant survival rates were high, an individualized assessment of risk-benefit balance is mandatory before indicating implant-based rehabilitation in patients suffering from systemic sclerosis and a scrupulous maintenance program has to be implemented. Further studies are strongly required to establish clinical guidelines.
系统性硬化症是一种罕见的多系统自身免疫性疾病，严重影响口腔颌面部。一些口腔特征，包括小口畸形和牙齿脱落增加，导致与口腔相关的残疾。在这些患者中，进行义齿修复极具挑战性。由于最近已将牙科种植体适应证的范围扩大到患有各种系统性疾病的患者，因此本系统评价旨在评估系统性硬化症患者的种植体治疗效果。在 Medline/PubMed 数据库中进行了文献检索，以确定合格的病例报告。在 10 名系统性硬化症患者中纳入了 10 项研究进行定性综合分析，共报告了 71 枚种植体，每位患者平均植入 7.1±3.8 枚。有 3 名患者进行了种植术前手术。种植体的存活率高于 98%，但平均随访时间仅为 28.3±18.6 个月。3 名患者出现并发症，1 例种植体失败，2 例出现种植体周围骨吸收。尽管种植体存活率较高，但在为系统性硬化症患者进行种植体修复之前，必须对风险效益平衡进行个体化评估，并实施严格的维护计划。需要进一步研究以制定临床指南。
