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Functional Gene Variants in Chronic Obstructive Pulmonary Disease: The Search Continues.

作者信息

Acunzo Mario, Nana-Sinkam Patrick

机构信息

Division of Pulmonary and Critical Care Medicine Virginia Commonwealth University Richmond, Virginia.

出版信息

Am J Respir Cell Mol Biol. 2021 Jul;65(1):8-9. doi: 10.1165/rcmb.2021-0169ED.

DOI:10.1165/rcmb.2021-0169ED
PMID:33945772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8320122/
Abstract
摘要

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本文引用的文献

1
Chromatin Landscapes of Human Lung Cells Predict Potentially Functional Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Variants.人类肺部细胞的染色质景观可预测潜在功能的慢性阻塞性肺疾病全基因组关联研究变异。
Am J Respir Cell Mol Biol. 2021 Jul;65(1):92-102. doi: 10.1165/rcmb.2020-0475OC.
2
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.慢性阻塞性肺疾病的遗传景观确定了不同的细胞类型和表型关联。
Nat Genet. 2019 Mar;51(3):494-505. doi: 10.1038/s41588-018-0342-2. Epub 2019 Feb 25.
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Integration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module.
整合分子互作组和靶向互作分析以识别 COPD 疾病网络模块。
Sci Rep. 2018 Sep 27;8(1):14439. doi: 10.1038/s41598-018-32173-z.
4
Whole-Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease.全基因组测序在严重慢性阻塞性肺疾病中的应用。
Am J Respir Cell Mol Biol. 2018 Nov;59(5):614-622. doi: 10.1165/rcmb.2018-0088OC.
5
Early Endotyping: A Chance for Intervention in Chronic Obstructive Pulmonary Disease.早期表型分型:慢性阻塞性肺疾病干预的机会。
Am J Respir Cell Mol Biol. 2018 Jul;59(1):13-17. doi: 10.1165/rcmb.2018-0002PS.
6
COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression.COPD GWAS 变异位于 19q13.2,与 DNA 甲基化和基因表达有关。
Hum Mol Genet. 2018 Jan 15;27(2):396-405. doi: 10.1093/hmg/ddx390.
7
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.与慢性阻塞性肺疾病相关的基因位点与肺功能及肺纤维化的基因位点重叠。
Nat Genet. 2017 Mar;49(3):426-432. doi: 10.1038/ng.3752. Epub 2017 Feb 6.
8
Beyond GWAS in COPD: probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks.慢性阻塞性肺疾病全基因组关联研究之外:探索基因集关联、全基因组关联和蛋白质-蛋白质相互作用网络之间的关系
Hum Hered. 2014;78(3-4):131-9. doi: 10.1159/000365589. Epub 2014 Aug 27.
9
Genome-wide association study of smoking behaviours in patients with COPD.COPD 患者吸烟行为的全基因组关联研究。
Thorax. 2011 Oct;66(10):894-902. doi: 10.1136/thoraxjnl-2011-200154. Epub 2011 Jun 16.
10
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.一项慢性阻塞性肺疾病(COPD)的全基因组关联研究:两个主要易感基因座的鉴定。
PLoS Genet. 2009 Mar;5(3):e1000421. doi: 10.1371/journal.pgen.1000421. Epub 2009 Mar 20.