School of Population Health, Curtin University, GPO Box U1987, Perth 6845, Western Australia, Australia.
Brain Cogn. 2021 Jul;151:105737. doi: 10.1016/j.bandc.2021.105737. Epub 2021 May 1.
A growing body of evidence suggests Chronic Lower Back Pain (CLBP) is associated with cognitive dysfunction. Little is known, however, about the extent of cognitive impairment in CLBP. The present study explored the cognitive profile of people with CLBP and sought to determine the extent of Mild Cognitive Impairment (MCI) according to the DSM-V and the Movement Disorders Society criteria for MCI. Thirty-one participants with CLBP and 27 age and gender matched healthy controls completed a full neuropsychological battery, consisting of two tasks for each of the five cognitive domains (Executive Function, Attention/Working Memory, Memory, Language, and Visuospatial). Participants with CLBP performed worse, compared to controls, on measures of Attention/Working Memory, Memory, Language, and Visuospatial performance. Cognitive performance in CLBP was also compared to equivalent normative data to determine cognitive impairment. Sixteen CLBP participants were impaired on at least one cognitive measure, with 5 participants meeting criteria for MCI. MCI was not associated with pain-related experience, or psychological health. The present study supports and extends previous findings that CLBP is associated with cognitive dysfunction and some people with CLBP meet criteria for MCI. These findings support that rehabilitation in people with CLBP requires a multidisciplinary approach.
越来越多的证据表明，慢性下腰痛（CLBP）与认知功能障碍有关。然而，人们对 CLBP 患者认知障碍的严重程度知之甚少。本研究探讨了 CLBP 患者的认知特征，并根据 DSM-V 和运动障碍协会的 MCI 标准，试图确定轻度认知障碍（MCI）的程度。31 名 CLBP 患者和 27 名年龄和性别匹配的健康对照者完成了完整的神经心理学测试，包括五个认知领域（执行功能、注意力/工作记忆、记忆、语言和视空间）的两个任务。与对照组相比，CLBP 患者在注意力/工作记忆、记忆、语言和视空间表现方面的表现更差。还将 CLBP 患者的认知表现与等效的规范数据进行比较，以确定认知障碍。16 名 CLBP 患者在至少一项认知测试中受损，5 名患者符合 MCI 标准。MCI 与疼痛相关体验或心理健康无关。本研究支持并扩展了之前的发现，即 CLBP 与认知功能障碍有关，一些 CLBP 患者符合 MCI 标准。这些发现支持 CLBP 患者的康复需要多学科方法。
