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开发一套核心的结局测量指标领域,以研究系统性硬化症中的雷诺现象和指(趾)溃疡:来自 OMERACT 2020 的报告。

Developing a core set of outcome measure domains to study Raynaud's phenomenon and digital ulcers in systemic sclerosis: Report from OMERACT 2020.

机构信息

Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.

Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

出版信息

Semin Arthritis Rheum. 2021 Jun;51(3):640-643. doi: 10.1016/j.semarthrit.2021.04.005. Epub 2021 Apr 21.

Abstract

Raynaud's phenomenon (RP) and digital ulcers (DUs) are important disease manifestations of systemic sclerosis (SSc) that can lead to significant pain and disability. It is essential when studying these disease features to utilize outcome measures that fully evaluate the complexities of RP and DUs . The Outcome Measures in Rheumatology (OMERACT) Vascular Disease in SSc Working Group is applying the OMERACT filter 2.1 to identify a core set of disease domains that encompass the full burden of SSc-related RP and DUs. Progress to date and future research plans were presented during a Special Interest Group held in December 2020.

摘要

雷诺现象(RP)和指(趾)溃疡(DU)是系统性硬化症(SSc)的重要疾病表现,可导致明显的疼痛和残疾。在研究这些疾病特征时,使用能够全面评估 RP 和 DU 复杂性的结果测量指标非常重要。风湿病结局测量(OMERACT)血管疾病 SSc 工作组正在应用 OMERACT 过滤器 2.1 来确定一组核心疾病域,这些疾病域包含 SSc 相关 RP 和 DU 的全部负担。在 2020 年 12 月举行的一次特别兴趣小组会议上介绍了迄今为止的进展和未来的研究计划。

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