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妊娠合并人工心脏瓣膜血栓形成：急性管理的病例系列。

Prosthetic heart valve thrombosis in pregnancy: a case series on acute management.

机构信息

Department of Obstetrics and Gynaecology, University of KwaZulu-Natal, Grey's Hospital, Pietermaritzburg, South Africa. Email:

Department of Obstetrics and Gynaecology, University of KwaZulu-Natal, Inkosi Albert Luthuli Central Hospital, Durban, South Africa.

出版信息

Cardiovasc J Afr. 2021;32(4):228-232. doi: 10.5830/CVJA-2021-013. Epub 2021 May 4.

DOI:10.5830/CVJA-2021-013
PMID:33950064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8756048/
Abstract

Rheumatic heart disease is one of the leading causes of valve dysfunction, resulting in prosthetic valve implantation. Changes in physiology and the haemodynamics of pregnancy increase the susceptibility of thrombosis to the prosthetic valve in the pregnant woman. Valve redo surgery carries a considerable risk of maternal and perinatal morbidity and mortality. Women of reproductive age should be well counselled regarding compliance with anticoagulation, contraception and pre-pregnancy planning.

摘要

风湿性心脏病是导致瓣膜功能障碍的主要原因之一，需要进行人工瓣膜植入。妊娠期间生理和血液动力学的变化会增加孕妇体内人工瓣膜发生血栓的易感性。再次进行瓣膜手术会给产妇和围产儿带来相当大的发病率和死亡率风险。应向育龄妇女提供有关抗凝治疗、避孕和孕前计划的充分咨询。

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