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使用超声评估声带和杓状软骨运动来诊断食管癌切除术后喉返神经麻痹。

Diagnosis of recurrent laryngeal nerve paralysis following esophagectomy by evaluating movement of the vocal cords and arytenoid cartilages using ultrasonography.

机构信息

Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Mizuho-cho, 1 Kawasumi, Mizuho-ku, Nagoya, Aichi, Japan.

出版信息

Esophagus. 2021 Jul;18(3):704-709. doi: 10.1007/s10388-021-00830-4. Epub 2021 May 5.

DOI:10.1007/s10388-021-00830-4
PMID:33950417
Abstract

Advancements in thoracoscopic surgery have provided us with a deeper anatomical understanding of recurrent laryngeal nerve paralysis (RLNP), which is likely to occur after lymph node dissection. Taking a novel approach to researching the diagnosis of RLNP, we evaluated movement of the vocal cords and arytenoid cartilages using ultrasonography in patients who underwent thoracoscopic esophagectomy. RLNP occurred in six of the 24 patient cohort. The rate of hoarseness and difficulty in discharging sputum was significantly higher in the paralyzed group than in the non-paralyzed group. The diagnostic accuracy of RLNP by ultrasonography had a sensitivity of 83.3% (5/6), a specificity of 88.8% (16/18), a false positive rate of 5.6% (1/18), and a false negative rate of 0% (0/6). Although it is not completely accurate, our findings indicate that ultrasonography is quite effective for diagnosing RLNP, more so in combination with clinical symptoms. Ultrasonography may also be effective for identifying patients who are amenable to laryngoscopy for diagnosing RLNP, or for evaluating the recovery status of nerve paralysis.

摘要

胸腔镜手术的进步使我们对喉返神经麻痹(RLNP)有了更深入的解剖学认识,这种情况可能发生在淋巴结清扫术后。我们采用一种新的方法来研究 RLNP 的诊断,对 24 例接受胸腔镜食管切除术的患者使用超声检查评估声带和杓状软骨的运动。在 24 例患者中有 6 例发生 RLNP。麻痹组的声音嘶哑和排痰困难发生率明显高于非麻痹组。超声检查对 RLNP 的诊断准确率为 83.3%(5/6),特异性为 88.8%(16/18),假阳性率为 5.6%(1/18),假阴性率为 0%(0/6)。虽然并不完全准确,但我们的研究结果表明,超声检查对于诊断 RLNP 非常有效,尤其是结合临床症状时。超声检查还可能有助于识别适合行喉镜诊断 RLNP 的患者,或评估神经麻痹的恢复情况。

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1
Diagnosis of recurrent laryngeal nerve paralysis following esophagectomy by evaluating movement of the vocal cords and arytenoid cartilages using ultrasonography.使用超声评估声带和杓状软骨运动来诊断食管癌切除术后喉返神经麻痹。
Esophagus. 2021 Jul;18(3):704-709. doi: 10.1007/s10388-021-00830-4. Epub 2021 May 5.
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引用本文的文献

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Long-term stimulation by implanted pacemaker enables non-atrophic treatment of bilateral vocal fold paresis in a human-like animal model.植入式起搏器的长期刺激可实现类似人类动物模型中双侧声带麻痹的非萎缩性治疗。
Sci Rep. 2024 May 7;14(1):10440. doi: 10.1038/s41598-024-60875-0.
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Refining postoperative monitoring of recurrent laryngeal nerve injury in esophagectomy patients through transcutaneous laryngeal ultrasonography.经皮喉超声检查术对食管癌术后喉返神经损伤的监测作用。
Esophagus. 2024 Apr;21(2):141-149. doi: 10.1007/s10388-023-01036-6. Epub 2023 Dec 22.
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A Prospective Study Evaluating the Feasibility and Accuracy of Post-operative Laryngeal Ultrasonography (LUSG) in Assessment of Vocal Cord Function After Esophagectomy.
一项评估术后喉超声(LUSG)用于评估食管癌术后声带功能的可行性和准确性的前瞻性研究。
World J Surg. 2023 Nov;47(11):2792-2799. doi: 10.1007/s00268-023-07128-9. Epub 2023 Aug 4.