Sheppard David P, Gallagher Matthew W, Morgan Erin E, Outlaw Angulique Y, Naar Sylvie, Woods Steven Paul
Department of Psychology, University of Houston, Houston, USA.
Veterans Affairs (VA) Northwest Network (VISN 20) Mental Illness, Research, Education, and Clinical Care (MIRECC), Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA.
J Int Neuropsychol Soc. 2022 Feb;28(2):166-176. doi: 10.1017/S1355617721000448. Epub 2021 May 6.
Memory symptoms and objective impairment are common in HIV disease and are associated with disability. A paradoxical issue is that objective episodic memory failures can interfere with accurate recall of memory symptoms. The present study assessed whether responses on a self-report scale of memory symptoms demonstrate measurement invariance in persons with and without objective HIV-associated memory impairment.
In total, 505 persons with HIV completed the Prospective and Retrospective Memory Questionnaire (PRMQ). Objective memory impairment (n = 141) was determined using a 1-SD cutoff on clinical tests of episodic memory. PRMQ measurement invariance was assessed by confirmatory factor analyses examining a one-factor model with increasing cross-group equality constraints imposed on factor loadings and item thresholds (i.e., configural, weak, and strong invariance).
Configural model fit indicated that identical items measured a one-factor model for both groups. Comparison to the weak model indicated that factor loadings were equivalent across groups. However, there was evidence of partial strong invariance, with two PRMQ item thresholds differing across memory impairment groups. Post hoc analyses using a 1.5-SD memory impairment cutoff (n = 77) revealed both partial weak and partial strong invariance, such that PRMQ item loadings differed across memory groups for three items.
The PRMQ demonstrated a robust factor structure among persons with and without objective HIV-associated memory impairment. However, on select PRMQ items, individuals with memory impairment reported observed scores that were relatively higher than their latent score, while items were more strongly associated with the memory factor in a group with greater memory impairment.
记忆症状和客观认知损害在HIV疾病中很常见,且与残疾相关。一个矛盾的问题是,客观的情景记忆失误会干扰对记忆症状的准确回忆。本研究评估了在有和没有与HIV相关的客观记忆损害的人群中,记忆症状自我报告量表的反应是否具有测量不变性。
共有505名HIV感染者完成了前瞻性和回顾性记忆问卷(PRMQ)。使用情景记忆临床测试中1个标准差的临界值来确定客观记忆损害(n = 141)。通过验证性因素分析评估PRMQ的测量不变性,该分析检验了一个单因素模型,对因素负荷和项目阈值施加了越来越多的跨组平等约束(即构型不变性、弱不变性和强不变性)。
构型模型拟合表明,相同的项目对两组都测量了一个单因素模型。与弱模型的比较表明,因素负荷在各组之间是等效的。然而,有证据表明存在部分强不变性,两个PRMQ项目阈值在记忆损害组之间存在差异。使用1.5个标准差的记忆损害临界值(n = 77)进行的事后分析显示了部分弱不变性和部分强不变性,即三个项目的PRMQ项目负荷在记忆组之间存在差异。
PRMQ在有和没有与HIV相关的客观记忆损害的人群中显示出稳健的因素结构。然而,在某些PRMQ项目上,记忆损害个体报告的观察分数相对高于其潜在分数,而在记忆损害程度较高的组中,这些项目与记忆因素的关联更强。