Finazzi Tobias, Schneiders Famke L, Senan Suresh
Clinic of Radiotherapy and Radiation Oncology, University Hospital Basel, Basel, Switzerland
Dept of Radiation Oncology, Amsterdam University Medical Centers, Location VUmc, Amsterdam, The Netherlands.
Eur Respir Rev. 2021 May 5;30(160). doi: 10.1183/16000617.0224-2020. Print 2021 Jun 30.
Radiation therapy is a cornerstone of modern lung cancer treatment alongside surgery, chemotherapy, immunotherapy and targeted therapies. Advances in radiotherapy techniques have enhanced the accuracy of radiation delivery, which has contributed to the evolution of radiation therapy into a guideline-recommended treatment in both early-stage and locally advanced nonsmall cell lung cancer. Furthermore, although radiotherapy has long been used for palliation of disease in advanced lung cancer, it is increasingly having a role as a locally ablative treatment in patients with oligometastatic disease.This review provides an overview of recent developments in radiation techniques, particularly for non-radiation oncologists who are involved in the care of lung cancer patients. Technical advances are discussed, and findings of recent clinical trials are highlighted, all of which have led to a changing perception of the role of radiation therapy in multidisciplinary care.
放射治疗是现代肺癌治疗的基石，与手术、化疗、免疫疗法和靶向治疗并驾齐驱。放射治疗技术的进步提高了放射剂量传递的准确性，这促使放射治疗在早期和局部晚期非小细胞肺癌中发展成为指南推荐的治疗方法。此外，尽管放射治疗长期以来一直用于晚期肺癌的姑息治疗，但在寡转移疾病患者中，它作为局部消融治疗的作用越来越大。本综述概述了放射技术的最新进展，特别是为参与肺癌患者护理的非放射肿瘤学家提供参考。文中讨论了技术进步，并强调了近期临床试验的结果，所有这些都导致了人们对放射治疗在多学科治疗中作用的看法发生了变化。
