Matsuda Tatsuo, Umeda Yuzo, Yoshida Kazuhiro, Matsuda Tadakazu, Uno Masatoshi, Abe Masaya, Asada Noboru, Maeda Yoshinobu, Yagi Takahito, Fujiwara Toshiyoshi
Department of Gastroenterological Surgery,Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Department of Surgery, Matsuda Hospital.
Acta Med Okayama. 2021 Apr;75(2):199-204. doi: 10.18926/AMO/61901.
We present the first case of laparoscopic left lateral segmentectomy for hepatocellular carcinoma (HCC) in a patient with hemophilia A, acquired hepatitis C, and high-titer factor VIII inhibitor, which was confirmed by preoperative diagnosis. He underwent laparoscopic left lateral segmentectomy with the administration of recombinant activated factor VII. Surgery could be performed with reduced intraoperative hemorrhage. He experienced postoperative intra-abdominal wall hemorrhage, which was successfully managed with red cell concentrates transfusion and administration of recombinant activated factor VII. Laparoscopic hepatectomy can be applied for hemophilia patients with high titer inhibitors.
我们报告了首例为一名患有甲型血友病、获得性丙型肝炎和高滴度凝血因子 VIII 抑制剂的肝细胞癌（HCC）患者实施腹腔镜左外叶切除术的病例，术前诊断得以证实。他接受了腹腔镜左外叶切除术，并给予重组活化凝血因子 VII。手术得以在减少术中出血的情况下进行。他术后出现腹壁内出血，通过输注红细胞浓缩液和给予重组活化凝血因子 VII 成功处理。腹腔镜肝切除术可应用于患有高滴度抑制剂的血友病患者。
