Azhar Aaminah Faheem, Saporito Rachael Camille, Jamerson Jordan
Texas A&M University College of Medicine, Bryan, Texas.
Department of Dermatology, Baylor Scott & White Medical Center - Temple, Temple, Texas.
Proc (Bayl Univ Med Cent). 2021 Mar 8;34(3):380-381. doi: 10.1080/08998280.2021.1877509.
Sorafenib, an oral chemotherapeutic agent used in the treatment of solid tumors, is associated with a variety of adverse cutaneous drug reactions in up to 90% of patients. Infrequently, delayed-type hypersensitivity reactions such as erythema multiforme occur. This case describes a child treated with sorafenib for a retrosternal desmoid tumor who developed widespread erythema multiforme across his extremities, trunk, face, and mucosal membranes.
索拉非尼是一种用于治疗实体瘤的口服化疗药物，高达90%的患者会出现各种皮肤药物不良反应。迟发型超敏反应如多形红斑较为罕见。本病例描述了一名因胸骨后硬纤维瘤接受索拉非尼治疗的儿童，其四肢、躯干、面部和黏膜出现广泛的多形红斑。
