Chatterjee Uday Sankar, Basu Ashoke Kumar, Mitra Debashis, Chatterjee Subir Kumar
Visiting Pediatric Surgeons, Department of Pediatric Surgery, Park Clinic, Kolkata, West Bengal, India.
J Indian Assoc Pediatr Surg. 2021 Jan-Feb;26(1):27-31. doi: 10.4103/jiaps.JIAPS_202_19. Epub 2021 Jan 11.
Split renal function (SFR) and frusemide washout (FWO) are assessed by the DTPA renogram to measure the renal parenchymal functions as well as the evidence of obstruction, both for diagnosis and to treat the pelviureteric junction obstruction. In good number of renal units, both these parameters remain unaltered even after surgery and cause anguish to parents and referring physicians and are usually attributed toward "defective pyeloplasty." In this study, we have tried to single out the bona fide responsible factor for the bad outcome; either the nonreversible kidney or the restenosis of pyeloplasty.
We studied file of 69 patients in whom a double "J" (DJ) stent was left for internal drainage for a duration of 8 weeks in the postoperative period. DTPA scans were performed preoperative, at 8 weeks with a stent in place, and at 12 and 24 months postremoval of the stent to assess renal function.
In our study, 45 patients (65.2%) showed improvement either in SRF or in FWO or in both after 8 weeks following pyeloplasty and 24 of 69 units (34.8%) did not show any change in renal function with DJ stent in place. Only in six units (8.7%), out of 69 units had deterioration of renal function after removal of DJ stent.
In our opinion, no improvement of renal function found in 24 units (34.8%) even with internal drainage with DJ indicates irreversible renal damage. In 45 units (65.2%), renal function reversed after pyeloplasty and DJ stent. However, after the removal of the DJ, functions deteriorated in six units (8.7%) due to restenosis following pyeloplasties.
通过二乙三胺五乙酸(DTPA)肾图评估分肾功能(SFR)和速尿清除率(FWO),以测量肾实质功能以及梗阻证据,用于诊断和治疗肾盂输尿管连接部梗阻。在相当数量的肾单位中,即使手术后这两个参数仍未改变,这让家长和转诊医生感到苦恼,通常被归因于“肾盂成形术缺陷”。在本研究中,我们试图找出导致不良结果的真正责任因素;是不可逆的肾脏问题还是肾盂成形术的再狭窄。
我们研究了69例患者的病历,这些患者在术后留置双“J”(DJ)支架进行内引流8周。在术前、支架在位8周时、支架取出后12个月和24个月进行DTPA扫描以评估肾功能。
在我们的研究中,45例患者(65.2%)在肾盂成形术后8周后分肾功能或速尿清除率或两者均有改善,69个肾单位中有24个(34.8%)在DJ支架在位时肾功能未显示任何变化。69个肾单位中只有6个(8.7%)在取出DJ支架后肾功能恶化。
我们认为,即使采用DJ内引流,仍有24个肾单位(34.8%)肾功能未改善,这表明存在不可逆的肾损伤。在45个肾单位(占65.2%)中,肾盂成形术和DJ支架置入后肾功能恢复正常。然而,取出DJ支架后,6个肾单位(8.7%)由于肾盂成形术后再狭窄,功能恶化。