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小儿腹腔镜Anderson-Hynes肾盂成形术后外置肾盂输尿管支架与内置双J输尿管支架的疗效及成本分析

Outcomes and costs analysis of Externalized PyeloUreteral versus internal Double-J ureteral stents after paediatric laparoscopic Anderson-Hynes pyeloplasty.

作者信息

Paraboschi Irene, Jannello Letizia, Mantica Guglielmo, Roberts Luke, Olubajo Seyi, Paul Anu, Mishra Pankaj, Taghizadeh Arash, Garriboli Massimo

机构信息

Paediatric Urology, Evelina London Children's Hospital, London, United Kingdom; DINOGMI University of Genoa, Genoa, Italy; Paediatric Surgery Unit, Giannina Gaslini Research Institute and Children Hospital, Genoa, Italy.

Paediatric Urology, Evelina London Children's Hospital, London, United Kingdom.

出版信息

J Pediatr Urol. 2021 Apr;17(2):232.e1-232.e7. doi: 10.1016/j.jpurol.2020.12.006. Epub 2020 Dec 8.

Abstract

BACKGROUND

The gold standard treatment for Uretero-Pelvic Junction Obstruction (UPJO) is laparoscopic dismembered pyeloplasty according to the Anderson-Hynes technique. The internal Double-J ureteral (DJ) and the Externalized PyeloUreteral (EPU) stents are usually the drainage of choice. Only a few articles have compared the clinical impact of the different drainage techniques on the perioperative morbidity and none presented a cost analysis of the incurred hospital stay.

OBJECTIVE

To present the clinical outcome and financial analysis of a cohort of children who underwent a laparoscopic pyeloplasty comparing the use of the DJ versus EPU stent.

STUDY DESIGN

Retrospective study of consecutives children who underwent laparoscopic Anderson-Hynes pyeloplasty in a single tertiary paediatric referral centre from January 2017 to March 2020. Patients were grouped according to the type of stent used: DJ stent vs EPU stent.

RESULTS

Fifty-three laparoscopic pyeloplasties were performed on 51 patients: 27 (50.9%) had an EPU stent and 26 (49.1%) a DJ stent. There was no statistically significant difference between the two patient groups with regards to surgical time, hospital stay, stent-related complications or the need for re-do surgery. All the EPU stents were removed with an outpatient admission 8.1 days ± 3.1 after surgery while the DJ stents were removed with a cystoscopy 61.6 days ± 30.2 after surgery (p value < 0.001). On a financial analysis (Figure), the hospital costs for stent removal were significantly lower for the EPU stent group (£ 686.7 ± 263.4 vs £ 1425 ± 299.5, p value < 0.01).

DISCUSSION

Both drainage methods have some disadvantages. Possible complications associated with DJ stents include migration and artificial vesicoureteral reflux which may lead to higher incidence of Urinary Tract Infections. Possible disadvantages of the EPU stent insertion are related to the damage of the renal parenchyma and to the risk of developing skin site infections and urinary leaks. However, in our series the EPU stent has not been associated with a higher incidence of bleeding, leakage or discomfort. In addition to clinical considerations, there is a financial implication to be considered. With this regard, the EPU stent was associated with a significant reduction in the incurred hospital costs.

CONCLUSIONS

The use of DJ and EPU stents is equivalent in regards of overall complications and success rates. DJ and EPU stents provided comparable success and complication rates, however the latter avoids the need of an additional general anaesthesia and reduces the overall incurred hospital costs.

摘要

背景

输尿管肾盂连接部梗阻(UPJO)的金标准治疗方法是根据安德森-海恩斯技术进行腹腔镜离断性肾盂成形术。内置双J输尿管(DJ)支架和外置肾盂输尿管(EPU)支架通常是首选的引流方式。只有少数文章比较了不同引流技术对围手术期发病率的临床影响,且没有一篇文章对住院费用进行成本分析。

目的

介绍一组接受腹腔镜肾盂成形术的儿童的临床结果和财务分析,比较DJ支架与EPU支架的使用情况。

研究设计

对2017年1月至2020年3月在一家三级儿科转诊中心接受腹腔镜安德森-海恩斯肾盂成形术的连续儿童进行回顾性研究。根据所用支架类型将患者分组:DJ支架组与EPU支架组。

结果

对51例患者进行了53次腹腔镜肾盂成形术:27例(50.9%)使用EPU支架,26例(49.1%)使用DJ支架。两组患者在手术时间、住院时间、支架相关并发症或再次手术需求方面无统计学显著差异。所有EPU支架在术后8.1天±3.1天门诊入院时取出,而DJ支架在术后61.6天±30.2天通过膀胱镜检查取出(p值<0.001)。在财务分析(图)中,EPU支架组的支架取出医院成本显著更低(686.7英镑±263.4英镑对1425英镑±299.5英镑,p值<0.01)。

讨论

两种引流方法都有一些缺点。与DJ支架相关的可能并发症包括移位和人为膀胱输尿管反流,这可能导致尿路感染的发生率更高。EPU支架置入的可能缺点与肾实质损伤以及发生皮肤部位感染和尿漏的风险有关。然而,在我们的系列研究中,EPU支架与出血、渗漏或不适的发生率较高无关。除了临床考虑外,还需要考虑财务影响。在这方面,EPU支架与住院费用的显著降低相关。

结论

在总体并发症和成功率方面,DJ支架和EPU支架的使用效果相当。DJ支架和EPU支架的成功率和并发症发生率相当,但后者避免了额外的全身麻醉需求并降低了总体住院费用。

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