Downie Samantha, Stillie Alison, Moran Matthew, Sudlow Cathie, Simpson Hamish
Orthopaedics and Trauma Department, The University of Edinburgh, Edinburgh.
NHS Lothian, Edinburgh.
Orthop Rev (Pavia). 2021 Mar 31;13(1):9062. doi: 10.4081/or.2021.9062. eCollection 2021 Mar 30.
Regardless of prognosis, surgery is often considered in metastatic bone disease (MBD) as a palliative procedure to improve function and quality of life. Traditional focus on objective outcomes such as mortality is inappropriate in this group, and there is a drive to assess outcomes via patient-reported outcome measures (PROMs). This is an overview of current understanding of MBD outcomes and how this should influence future decision-making and research. The objectives of this review were to identify difficulties in measuring PROMs in the MBD patient population and explore alternatives to patientreported outcomes. We also provide an overview of current understanding of outcomes in MBD and how this should influence decision-making and direct research.
无论预后如何,手术在转移性骨病(MBD)中通常被视为一种姑息性治疗手段,以改善功能和生活质量。在这一群体中,传统上关注诸如死亡率等客观结果是不合适的,目前有一种通过患者报告结局量表(PROMs)来评估结局的趋势。本文概述了目前对MBD结局的理解,以及这应如何影响未来的决策和研究。本综述的目的是确定在MBD患者群体中测量PROMs的困难,并探索患者报告结局的替代方法。我们还概述了目前对MBD结局的理解,以及这应如何影响决策和指导研究。