Institute for Signal Processing, University of Luebeck, Luebeck, Germany.
Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA.
Magn Reson Med. 2021 Sep;86(3):1701-1717. doi: 10.1002/mrm.28813. Epub 2021 May 6.
To improve the robustness of diffusion-weighted imaging (DWI) data acquired with segmented simultaneous multi-slice (SMS) echo-planar imaging (EPI) against in-plane and through-plane rigid motion.
The proposed algorithm incorporates a 3D rigid motion correction and wavelet denoising into the image reconstruction of segmented SMS-EPI diffusion data. Low-resolution navigators are used to estimate shot-specific diffusion phase corruptions and 3D rigid motion parameters through SMS-to-volume registration. The shot-wise rigid motion and phase parameters are integrated into a SENSE-based full-volume reconstruction for each diffusion direction. The algorithm is compared to a navigated SMS reconstruction without gross motion correction in simulations and in vivo studies with four-fold interleaved 3-SMS diffusion tensor acquisitions.
Simulations demonstrate high fidelity was achieved in the SMS-to-volume registration, with submillimeter registration errors and improved image reconstruction quality. In vivo experiments validate successful artifact reduction in 3D motion-compromised in vivo scans with a temporal motion resolution of approximately 0.3 s.
This work demonstrates the feasibility of retrospective 3D rigid motion correction from shot navigators for segmented SMS DWI.
提高分段同时多层（SMS）回波平面成像（EPI）扩散加权成像（DWI）数据对平面内和平面外刚性运动的鲁棒性。
所提出的算法将 3D 刚性运动校正和小波去噪纳入分段 SMS-EPI 扩散数据的图像重建中。使用低分辨率导航仪通过 SMS 到体积配准来估计特定于射门的扩散相位失真和 3D 刚性运动参数。针对每个扩散方向，将逐拍刚性运动和相位参数集成到基于 SENSE 的全体积重建中。该算法在模拟和具有四倍交错 3-SMS 扩散张量采集的体内研究中与未经大体运动校正的导航 SMS 重建进行了比较。
模拟表明，SMS 到体积配准中实现了高保真度，具有亚毫米级的配准误差和改进的图像重建质量。体内实验验证了在具有约 0.3 s 的时间运动分辨率的 3D 运动受限体内扫描中成功减少了伪影。
这项工作证明了从分段 SMS DWI 的射弹导航器进行回顾性 3D 刚性运动校正的可行性。
