Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, China.
Department of Clinical Laboratory, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, China.
Orthop Surg. 2021 Jun;13(4):1452-1457. doi: 10.1111/os.12904. Epub 2021 May 6.
Wear debris pseudotumors are a rare complication after total knee arthroplasty (TKA) and have seldom been reported in the recent literature. There is no consensus on the best therapeutic method, but the high quality curative treatment, safe, low invasive treatments are required for the patients.
In this paper, we present the case of a 74-year-old man with a wear debris pseudotumor after TKA with symptoms of severe pain and functional disability of his right knee. X-ray examination showed that the medial compartment of the right knee was narrowing. Magnetic resonance imaging (MRI) and Doppler ultrasound both revealed a polycystic mass at the posteromedial side of the patient's right knee. Considering the bad health condition and the minimally invasive surgery requirement of this senior patient, arthroscopic knee debridement and percutaneous cystic mass suction were carried out simultaneously. Video arthroscopy of the right knee showed visible inflammatory soft tissue, obvious polyethylene fragments, wear of the polyethylene prothesis, and a broken polyethylene insert. The intraarticular polyethylene wear debris was removed as much as possible, and inflammatory soft tissue was debrided and sent for pathology. Postoperative pathology showed polyethylene debris in the soft tissue with an apparent multinucleated giant cell response, which was consistent with foreign body granuloma. All clinical manifestation was improved and Lysholm scores were significantly better at one year with this treatment, increasing from 32 points to 71 points.
After two years of follow-up, the patient's knee joint was significantly relieved from soreness and pain, and walking was not significantly restricted. Our treatment could not address the root cause of the wear debris pseudotumor, which was due to prosthesis failure, but sometimes, such an approach is the safest, most economical, and most effective choice for patients who are intolerant to reoperation.
磨损颗粒性假瘤是全膝关节置换术后(TKA)一种罕见的并发症,在近期文献中鲜有报道。对于这种并发症,目前还没有最佳的治疗方法,但需要为患者提供高质量的治疗、安全、微创的治疗。
本文报道了 1 例 74 岁男性 TKA 后出现磨损颗粒性假瘤的病例,该患者的右膝关节出现严重疼痛和功能障碍等症状。X 射线检查显示右膝关节内侧间隙变窄。磁共振成像(MRI)和多普勒超声均显示患者右膝关节后内侧有一多房性肿块。考虑到该老年患者的健康状况不佳,以及微创手术的需求,同时进行了关节镜膝关节清创术和经皮囊状肿块抽吸术。右膝关节视频关节镜检查显示可见炎性软组织,明显的聚乙烯碎片,聚乙烯假体磨损和破碎的聚乙烯插入物。尽可能多地清除关节内聚乙烯磨损碎屑,同时切除炎性软组织并送检病理。术后病理显示软组织内有聚乙烯碎屑,有明显的多核巨细胞反应,符合异物肉芽肿。经过这种治疗后,所有的临床表现均得到改善,Lysholm 评分在 1 年时明显提高,从 32 分提高到 71 分。
随访 2 年后,患者膝关节疼痛明显缓解,行走无明显受限。我们的治疗无法解决因假体失败导致的磨损颗粒性假瘤的根本原因,但有时,对于不耐受再次手术的患者,这种方法是最安全、最经济和最有效的选择。