Department of Translational Research, Western University of Health Sciences, Pomona, CA, USA.
J Mater Sci Mater Med. 2021 May 6;32(5):54. doi: 10.1007/s10856-021-06520-y.
Demand for donor hearts has increased globally due to cardiovascular diseases. Recently, three-dimensional (3D) bioprinting technology has been aimed at creating clinically viable cardiac constructs for the management of myocardial infarction (MI) and associated complications. Advances in 3D bioprinting show promise in aiding cardiac tissue repair following injury/infarction and offer an alternative to organ transplantation. This article summarizes the basic principles of 3D bioprinting and recent attempts at reconstructing functional adult native cardiac tissue with a focus on current challenges and prospective strategies.
由于心血管疾病，全球对供体心脏的需求不断增加。最近，三维（3D）生物打印技术旨在为心肌梗死（MI）和相关并发症的管理创建临床可行的心脏构建体。3D 生物打印的进步有望帮助受伤/梗塞后的心脏组织修复，并为器官移植提供替代方案。本文总结了 3D 生物打印的基本原理，以及最近用其重建功能性成人原生心脏组织的尝试，重点介绍了当前的挑战和未来的策略。
