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经动脉注射氰基丙烯酸正丁酯栓塞术治疗多发伤患者腹腔盆腔活动性出血

Transarterial embolization with n-butyl cyanoacrylate for the treatment of active abdominopelvic bleeding in the polytraumatized patient.

作者信息

de Freitas Rafael Kiyuze, Monsignore Lucas Moretti, Castro-Afonso Luis Henrique de, Nakiri Guilherme Seizem, Elias-Junior Jorge, Muglia Valdair Francisco, Scarpelini Sandro, Abud Daniel Giansante

机构信息

Division of Interventional Radiology, Department of Radiology, Hematology and Oncology, Medical School of Ribeirão Preto, University of São Paulo, Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, SP, 14048-090, Brazil.

Division of Abdominal Radiology, Department of Radiology, Hematology and Oncology, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

出版信息

CVIR Endovasc. 2021 May 6;4(1):39. doi: 10.1186/s42155-021-00222-w.

Abstract

PURPOSE

An increasing number of polytraumatized patient presenting with active abdominal pelvic bleeding (APB) have been treated by endovascular selective embolization. However, reports on evaluate the efficacy, safety and complications caused by this technique have been limited. The aim of this study was to assess the safety and efficacy of embolization of APB using N-butyl cyanoacrylate glue (NBCA).

MATERIALS AND METHODS

Single center retrospective study, that included consecutive 47 patients presenting with traumatic APB treated by embolization with NBCA between January 2013 and June 2019. The efficacy endpoint was defined as the absence of contrast extravasation immediately after procedure and clinical stabilization in the following 24 h after procedure. Clinical stabilization was defined as no rebleeding after embolization or the need for a surgical approach until the patient is discharged. Safety endpoint were any technical or clinical complications related to the embolization procedure.

RESULTS

The mean age of patients was 38.6 years (3-81), with a predominance of males (87.2%). The major causal factor of APB being involvement in a car accident, accounting for 68% of cases. Of the 47 cases, 29.8% presented pelvic trauma and the remaining (70.2%) presented abdominal trauma. The efficacy rate was 100%, while no complications related to the procedure were observed. The mortality rate was 14.8% (7/47) due to neurologic decompensation and other clinical causes.

CONCLUSION

Endovascular embolization of traumatic abdominopelvic bleedings appear to be a highly safe and effective treatment, while avoiding emergent exploratory open surgeries.

摘要

目的

越来越多伴有腹腔盆腔活动性出血(APB)的多发伤患者接受了血管内选择性栓塞治疗。然而,关于评估该技术的疗效、安全性和并发症的报告有限。本研究的目的是评估使用氰基丙烯酸正丁酯胶(NBCA)栓塞APB的安全性和疗效。

材料与方法

单中心回顾性研究,纳入了2013年1月至2019年6月间连续47例接受NBCA栓塞治疗的创伤性APB患者。疗效终点定义为术后即刻无造影剂外渗且术后24小时内临床稳定。临床稳定定义为栓塞后无再出血或直至患者出院无需手术治疗。安全终点为与栓塞手术相关的任何技术或临床并发症。

结果

患者的平均年龄为38.6岁(3 - 81岁),男性占主导(87.2%)。APB的主要病因是交通事故,占病例的68%。47例中,29.8%有骨盆创伤,其余(70.2%)有腹部创伤。有效率为100%,未观察到与手术相关的并发症。由于神经功能失代偿和其他临床原因,死亡率为14.8%(7/47)。

结论

创伤性腹腔盆腔出血的血管内栓塞似乎是一种高度安全有效的治疗方法,同时避免了紧急探查性开放手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90d1/8102658/aafa5d46700a/42155_2021_222_Fig1_HTML.jpg

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