Ludewig R, Böhme H R
Z Gesamte Inn Med. 1977 Aug 15;32(16):401-6.
An extensive literature on influencing laboratory diagnostics by drugs gave rise to uncertainty in interpretation of clinico-chemical results. However, a critical revision of primary literature shows that at this time only a relatively small part of asserted influence is secured and relevant for the therapeutic situation in human being. In interest of the interpretation of the results as well as of the early diagnosis of biochemically conceivable side-effects of drugs and poisonings systemic clinico-pharmacological and clinico-chemical investigations are necessary. For a rough orientation in patients some tables were added in extracts taking as a basis a critical selection of hitherto existing literature on such influences.
大量关于药物对实验室诊断影响的文献使得临床化学结果的解读存在不确定性。然而,对原始文献的严格审查表明,目前只有相对较小一部分所声称的影响得到证实且与人类治疗情况相关。为了准确解读结果以及早期诊断药物和中毒在生化方面可能出现的副作用,进行系统的临床药理学和临床化学研究是必要的。为了帮助医生大致了解情况,我们从现有的关于此类影响的文献中进行了严格筛选,提取了一些表格作为参考。