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特发性炎性肌病患者的性功能：一项横断面研究。

Sexual function in patients with idiopathic inflammatory myopathies: a cross-sectional study.

机构信息

Department of Physiotherapy, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic.

Institute of Rheumatology, Prague, Czech Republic.

出版信息

Rheumatology (Oxford). 2021 Nov 3;60(11):5060-5072. doi: 10.1093/rheumatology/keab397.

DOI:10.1093/rheumatology/keab397
PMID:33956947
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8566285/
Abstract

OBJECTIVES

To date, there is almost no information concerning the sexual health of patients with idiopathic inflammatory myopathies (IIM). This cross-sectional study aimed to compare sexual function in patients with IIM to age-/sex-matched healthy controls (HC) and determine the potential impact of clinical features on sexual function.

METHODS

In total, 122 women (61 with IIM, 61 age-matched HC) and 22 men (11 with IIM, 11 age-matched HC) aged 18-80 years completed gender-specific selection of 7 well-established and validated questionnaires assessing sexual health and function (Female Sexual Function Index, Brief Index of Sexual Function for Women, Sexual Function Questionnaire, Sexual Quality of Life Questionnaire-Female, International Index of Erectile Function, Male Sexual Health Questionnaire, Sexual Quality of Life Questionnaire-Male). Results were compared between patients and HC and correlated with selected disease-related features.

RESULTS

The prevalence of sexual dysfunction in IIM was 59% in women (vs 40% in HC), and 64% (vs 9% in HC) in men. Men and women with IIM reported significantly impaired sexual function compared with sex-/age-matched HC. Decreased sexual function was associated with muscle weakness, disability, physical inactivity, fatigue, depression and decreased quality of life.

CONCLUSIONS

Our results suggest that sexual dysfunction is common among IIM patients and more attention should be paid to this aspect of the disease.

摘要

目的

迄今为止，关于特发性炎性肌病（IIM）患者的性健康几乎没有任何信息。本横断面研究旨在比较 IIM 患者的性功能与年龄/性别匹配的健康对照组（HC），并确定临床特征对性功能的潜在影响。

方法

共有 122 名年龄在 18-80 岁的女性（61 名患有 IIM，61 名年龄匹配的 HC）和 22 名男性（11 名患有 IIM，11 名年龄匹配的 HC）完成了 7 种经过充分验证的特定性别问卷，用于评估性健康和功能（女性性功能指数、女性简短性功能指数、性功能问卷、女性性健康生活质量问卷、国际勃起功能指数、男性性健康问卷、男性性健康生活质量问卷）。将患者和 HC 的结果进行比较，并与选定的疾病相关特征相关联。

结果

IIM 患者中性功能障碍的患病率为 59%（HC 为 40%），男性为 64%（HC 为 9%）。与年龄/性别匹配的 HC 相比，患有 IIM 的男性和女性报告的性功能明显受损。性功能下降与肌肉无力、残疾、身体活动减少、疲劳、抑郁和生活质量下降有关。

结论

我们的结果表明，性功能障碍在 IIM 患者中很常见，应更加关注该疾病的这一方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f107/8566285/79e82900e6f1/keab397f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f107/8566285/b90994933fac/keab397f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f107/8566285/79e82900e6f1/keab397f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f107/8566285/b90994933fac/keab397f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f107/8566285/79e82900e6f1/keab397f2.jpg

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