Toh James Wei Tatt, Cecire Jack, Hitos Kerry, Shedden Karen, Gavegan Fiona, Pathmanathan Nimalan, El Khoury Toufic, Di Re Angelina, Cocco Annelise, Limmer Alex, Liang Tom, Fok Kar Yin, Rogers James, Solis Edgardo, Ctercteko Grahame
Discipline of Surgery, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.
Department of Surgery, Westmead Hospital, Westmead, NSW, Australia.
Ann Coloproctol. 2022 Feb;38(1):36-46. doi: 10.3393/ac.2020.11.23. Epub 2021 May 6.
Enhanced Recovery After Surgery (ERAS) has become standard of care in colorectal surgery. However, there is not a universally accepted colorectal ERAS protocol and significant variations in care exist between institutions. The aim of this study was to examine the impact of variations in ERAS interventions and complications on length of stay (LOS).
This study was a single-center review of the first 200 consecutive patients recruited into our prospectively collected ERAS database. The primary outcome of this study was to examine the rate of compliance to ERAS interventions and the impact of these interventions on LOS. The secondary outcome was to assess the impact of complications (anastomotic leak, ileus, and surgical site infections) on LOS. ERAS interventions, rate of adherence, LOS, readmissions, morbidity, and mortality were recorded, and statistical analysis was performed.
ERAS variations and complications significantly influenced patient LOS on both univariate and multivariate analysis. ERAS interventions identified as the most important strategies in reducing LOS included laparoscopic surgery, mobilization twice daily postoperative day (POD) 0 to 1, discontinuation of intravenous fluids on POD 0 to 1, upgrading to solid diet by POD 0 to 2, removal of indwelling catheter by POD 0 to 2, avoiding nasogastric tube reinsertion and removing drains early. Both major and minor complications increased LOS. Anastomotic leak and ileus were associated with the greatest increase in LOS.
Seven high-yield ERAS interventions reduced LOS. Major and minor complications increased LOS. Reducing variations in care and complications can improve outcomes following colorectal surgery.
术后加速康复(ERAS)已成为结直肠手术的护理标准。然而,目前尚无普遍接受的结直肠ERAS方案,各机构之间的护理存在显著差异。本研究的目的是探讨ERAS干预措施和并发症的差异对住院时间(LOS)的影响。
本研究是对前瞻性收集的ERAS数据库中连续招募的前200例患者进行的单中心回顾性研究。本研究的主要结果是检查ERAS干预措施的依从率以及这些干预措施对住院时间的影响。次要结果是评估并发症(吻合口漏、肠梗阻和手术部位感染)对住院时间的影响。记录ERAS干预措施、依从率、住院时间、再入院率、发病率和死亡率,并进行统计分析。
在单因素和多因素分析中,ERAS差异和并发症均显著影响患者的住院时间。被确定为缩短住院时间最重要策略的ERAS干预措施包括腹腔镜手术、术后第0至1天每天两次活动、术后第0至1天停止静脉输液、术后第0至2天升级为固体饮食、术后第0至2天拔除留置导管、避免重新插入鼻胃管并尽早拔除引流管。主要和次要并发症均延长了住院时间。吻合口漏和肠梗阻与住院时间延长的相关性最大。
七种高效的ERAS干预措施可缩短住院时间。主要和次要并发症均延长了住院时间。减少护理差异和并发症可改善结直肠手术后的结局。