Aires-Moreno Giulyane Targino, Alcântara Thaciana Dos Santos, Araújo Dyego Carlos Souza Anacleto de, Soares Simony da Mota, Gubert Vanessa Terezinha, Marcon de Oliveira Vanessa, Ferreira Cristiane Munaretto, Vasconcelos-Pereira Erica Freire, Lira Ana Rafaela Pires, Chemello Clarice, Oliveira Layse Maria Soares de, Oliveira-Filho Alfredo Dias de, Lyra Divaldo
Laboratory of Teaching and Research in Social Pharmacy (LEPFS), Department of Pharmacy, Federal University of Sergipe, Sao Cristóvão, Brazil.
University Hospital, Federal University of Sergipe, Sao Cristóvão, Brazil.
Arch Dis Child. 2021 Oct;106(10):1018-1023. doi: 10.1136/archdischild-2020-320225. Epub 2021 May 6.
To determine the incidence of medication discrepancies in transition points of care of hospitalised children.
A prospective observational multicentre study was carried out between February and August 2019. Data collection consisted of the following steps: sociodemographic data collection, clinical interview with the patient's caregiver, review of patient prescriptions and evaluation of medical records. Medication discrepancies were classified as intentional (documented or undocumented) and unintentional. In addition, discrepancies identified were categorised according to the medication discrepancy taxonomy. Unintentional discrepancies were assessed for potential clinical harm to the patient.
Paediatric clinics of four teaching hospitals in Brazil.
Children aged 1 month-12 years.
A total of 248 children were included, 77.0% (n=191) patients had at least one intentional discrepancy; 20.2% (n=50) patients had at least one unintended discrepancy and 15.3% (n=38) patients had at least one intentional discrepancy and an unintentional one. The reason for the intentional discrepancy was not documented in 49.6% (n=476) of the cases. The most frequent unintentional discrepancy was medication omission (54.1%; n=66). Low potential to cause discomfort was found in 53 (43.4%) unintentional discrepancies, while 55 (45.1%) had the potential to cause moderate discomfort and 14 (11.5%) could potentially cause severe discomfort.
Although most medication discrepancies were intentional, the majority of these were not documented by the healthcare professionals. Unintentional discrepancies were often related to medication omission and had a potential risk of causing harm to hospitalised children.
确定住院儿童护理转接点处用药差异的发生率。
2019年2月至8月进行了一项前瞻性观察性多中心研究。数据收集包括以下步骤：社会人口统计学数据收集、与患者照顾者的临床访谈、患者处方审查和病历评估。用药差异分为有意（有记录或无记录）和无意两类。此外，根据用药差异分类法对识别出的差异进行分类。对无意差异评估其对患者的潜在临床危害。
巴西四家教学医院的儿科诊所。
1个月至12岁的儿童。
共纳入248名儿童，77.0%（n = 191）的患者至少有一处有意差异；20.2%（n = 50）的患者至少有一处无意差异，15.3%（n = 38）的患者至少有一处有意差异和一处无意差异。49.6%（n = 476）的病例未记录有意差异的原因。最常见的无意差异是漏服药物（54.1%；n = 66）。53例（43.4%）无意差异导致不适的可能性较低，55例（45.1%）可能导致中度不适，14例（11.5%）可能导致严重不适。
虽然大多数用药差异是有意的，但这些差异中的大多数未被医护人员记录。无意差异通常与漏服药物有关，对住院儿童有潜在危害风险。
