Poppema S, Postma L, Brinker M, de Jong B
Department of Pathology, University of Groningen, The Netherlands.
Cancer. 1988 Aug 15;62(4):791-4. doi: 10.1002/1097-0142(19880815)62:4<791::aid-cncr2820620425>3.0.co;2-m.
Complete spontaneous regression of high-grade malignant non-Hodgkin's lymphoma is extremely unusual. In this report the authors describe a complete spontaneous remission after surgical excisional biopsy of a small noncleaved cell malignant lymphoma (non-Burkitt's lymphoblastic lymphoma) of the tonsil in a 12-year-old boy. The diagnosis was confirmed by immunohistologic and immunoglobulin gene analysis. Similar studies were performed on the cervical lymph node excised 2 weeks later when spontaneous remission had occurred. The patient has remained in good health for over 3 years.
高度恶性非霍奇金淋巴瘤完全自发消退极为罕见。在本报告中，作者描述了一名12岁男孩扁桃体小无裂细胞恶性淋巴瘤（非伯基特淋巴母细胞淋巴瘤）经手术切除活检后完全自发缓解的病例。诊断通过免疫组织学和免疫球蛋白基因分析得以证实。在自发缓解发生2周后切除的颈部淋巴结上进行了类似研究。该患者已保持健康超过3年。
