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关节内动脉栓塞治疗全膝关节置换术后难治性关节积血:技术、安全性、疗效和患者报告的结果。

Genicular Artery Embolization for Refractory Hemarthrosis following Total Knee Arthroplasty: Technique, Safety, Efficacy, and Patient-Reported Outcomes.

机构信息

Department of Radiology, Division of Interventional Radiology, NewYork-Presbyterian/Weill Cornell Medical Center, New York, New York.

Department of Radiology, Division of Interventional Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.

出版信息

J Vasc Interv Radiol. 2021 Aug;32(8):1128-1135. doi: 10.1016/j.jvir.2021.04.020. Epub 2021 May 5.

Abstract

PURPOSE

To investigate the safety and efficacy of genicular artery embolization for treatment of refractory hemarthrosis following total knee arthroplasty.

MATERIAL AND METHODS

Patients who underwent genicular artery embolization with spherical embolics between January 2010 and March 2020 at a single institution were included if they had undergone total knee arthroplasty and subsequently experienced recurrent hemarthrosis. Technical success was defined as the significant reduction or elimination of the hyperemic blush. Clinical success was defined as the absence of clinical evidence of further hemarthrosis. Clinical follow-up was performed 7-14 days after the procedure and at 3-month intervals thereafter via a telephone interview. A total of 117 embolizations, comprising 82 initial, 28 first repeat, and 7 second repeat, were performed.

RESULTS

An average of 2.5 arteries was treated per procedure. The superior lateral genicular artery was the most frequently embolized. The most utilized embolic size was 100-300 μm. Follow-up was available for all patients, with a median duration of 21.5 months. 65.9%, 25.6%, and 8.5% of patients underwent 1, 2, and 3 treatments, respectively. Complications occurred following 12.8% of treatments, of which the most common was transient cutaneous ischemia. Technical success was achieved in all cases. Clinical success was achieved in 56%, 79%, and 85% of patients following the first, second, and third treatment, respectively. 83% of patients reported being either satisfied or very satisfied with the overall result.

CONCLUSIONS

Targeted genicular artery embolization with spherical embolics is an effective treatment for recurrent hemarthrosis with infrequent serious complications. Repeat embolization should be considered in cases of recurrence following initial therapy.

摘要

目的

研究膝关节炎全膝关节置换术后难治性关节积血行关节内动脉栓塞治疗的安全性和有效性。

材料与方法

2010 年 1 月至 2020 年 3 月,在一家机构接受球形栓塞物关节内动脉栓塞治疗的患者,如果他们已经接受了全膝关节置换术,随后出现复发性关节积血,则纳入研究。技术成功定义为明显减少或消除充血性红晕。临床成功定义为无进一步关节积血的临床证据。临床随访在手术后 7-14 天及此后每 3 个月通过电话访谈进行。共进行了 117 次栓塞术,包括 82 次初次治疗、28 次第一次重复治疗和 7 次第二次重复治疗。

结果

每次手术平均处理 2.5 条动脉。最常栓塞的是膝外上侧动脉。最常用的栓塞尺寸为 100-300μm。所有患者均获得随访,中位随访时间为 21.5 个月。分别有 65.9%、25.6%和 8.5%的患者接受了 1、2 和 3 次治疗。12.8%的治疗出现了并发症,最常见的是短暂性皮肤缺血。所有病例均达到技术成功。初次治疗后,分别有 56%、79%和 85%的患者达到临床成功。83%的患者报告对总体结果满意或非常满意。

结论

用球形栓塞物进行有针对性的关节内动脉栓塞治疗复发性关节积血是一种有效的方法,并发症罕见且严重。初次治疗后复发的患者应考虑重复栓塞治疗。

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