Macki Mohamed, Hamilton Travis, Lim Seokchun, Telemi Edvin, Bazydlo Michael, Nerenz David R, Zakaria Hesham Mostafa, Schultz Lonni, Khalil Jad G, Perez-Cruet Miguelangelo J, Aleem Ilyas S, Park Paul, Schwalb Jason M, Abdulhak Muwaffak M, Chang Victor
1Department of Neurosurgery, Henry Ford Hospital, Detroit.
Departments of2Orthopaedic Surgery and.
J Neurosurg Spine. 2021 May 7;35(1):91-99. doi: 10.3171/2020.10.SPINE20914. Print 2021 Jul 1.
Most studies on racial disparities in spine surgery lack data granularity to control for both comorbidities and self-assessment metrics. Analyses from large, multicenter surgical registries can provide an enhanced platform for understanding different factors that influence outcome. In this study, the authors aimed to determine the effects of race on outcomes after lumbar surgery, using patient-reported outcomes (PROs) in 3 areas: the North American Spine Society patient satisfaction index, the minimal clinically important difference (MCID) on the Oswestry Disability Index (ODI) for low-back pain, and return to work.
The Michigan Spine Surgery Improvement Collaborative was queried for all elective lumbar operations. Patient race/ethnicity was categorized as Caucasian, African American, and "other." Measures of association between race and PROs were calculated with generalized estimating equations (GEEs) to report adjusted risk ratios.
The African American cohort consisted of a greater proportion of women with the highest comorbidity burden. Among the 7980 and 4222 patients followed up at 1 and 2 years postoperatively, respectively, African American patients experienced the lowest rates of satisfaction, MCID on ODI, and return to work. Following a GEE, African American race decreased the probability of satisfaction at both 1 and 2 years postoperatively. Race did not affect return to work or achieving MCID on the ODI. The variable of greatest association with all 3 PROs at both follow-up times was postoperative depression.
While a complex myriad of socioeconomic factors interplay between race and surgical success, the authors identified modifiable risk factors, specifically depression, that may improve PROs among African American patients after elective lumbar spine surgery.
大多数关于脊柱手术种族差异的研究缺乏数据粒度,无法同时控制合并症和自我评估指标。来自大型多中心手术登记处的分析可以为理解影响手术结果的不同因素提供一个更好的平台。在本研究中,作者旨在利用北美脊柱协会患者满意度指数、下腰痛Oswestry功能障碍指数(ODI)的最小临床重要差异(MCID)以及重返工作岗位这三个领域的患者报告结局(PROs),确定种族对腰椎手术后结局的影响。
查询密歇根脊柱手术改善协作组织的所有择期腰椎手术病例。患者种族/族裔分为白种人、非裔美国人以及“其他”。采用广义估计方程(GEEs)计算种族与PROs之间的关联度,以报告调整后的风险比。
非裔美国人队列中女性比例更高,合并症负担也最重。在术后1年和2年分别随访的7980例和4222例患者中,非裔美国人患者的满意度、ODI的MCID以及重返工作岗位的比例最低。经过GEE分析,非裔美国人种族降低了术后1年和2年的满意度概率。种族并未影响重返工作岗位或ODI达到MCID。在两个随访时间点,与所有3个PROs关联度最大的变量是术后抑郁。
虽然种族与手术成功之间存在复杂多样的社会经济因素相互作用,但作者确定了一些可改变的风险因素,特别是抑郁,这可能会改善非裔美国人患者择期腰椎脊柱手术后的PROs。