van Staveren Irene
Institute of Social Studies, Erasmus University Rotterdam, Kortenaerkade 12, 2518 AX, The Hague, The Netherlands.
BMC Res Notes. 2021 May 8;14(1):174. doi: 10.1186/s13104-021-05587-8.
The data collected by the Global Burden of Disease 2016 project indicate that migraine ranks second in high-income countries with very competitive and flexible labour markets, and first in low- and middle-income countries suffering from civic unrest and conflict. This raises the question whether external stress factors may be correlated with migraine years lived with disability per 100,000 inhabitants (YLD). The objective of this exploratory study is to test the hypothesis that external stress factors are correlated with the prevalence and severity of migraine at the country level. The analysis uses two country groups: developed and developing countries. For the first group, the proxy variables for stress are labour productivity and unemployment rate. For the second group, the proxy variables measure conflict-related deaths and share of migrant/refugee population.
The results show a positive relationship between the stress variables on the one hand and migraine YLD on the other hand for both country groups. Almost all results are statistically significant at p < 0.01. These exploratory findings suggest that societal stress factors may be potential candidates for modifiable factors for the prevalence and/or severity of migraine at the country level.
全球疾病负担2016项目收集的数据表明，在劳动力市场极具竞争力且灵活的高收入国家中，偏头痛位列第二；而在遭受内乱和冲突的低收入和中等收入国家中，偏头痛则位居榜首。这就引发了一个问题，即外部压力因素是否可能与每10万居民的偏头痛残疾生存年数（YLD）相关。这项探索性研究的目的是检验外部压力因素与国家层面偏头痛患病率及严重程度相关这一假设。该分析采用了两个国家组：发达国家和发展中国家。对于第一组，压力的代理变量是劳动生产率和失业率。对于第二组，代理变量衡量与冲突相关的死亡人数以及移民/难民人口比例。
结果显示，对于这两个国家组而言，一方面压力变量与另一方面的偏头痛YLD之间存在正相关关系。几乎所有结果在p < 0.01时均具有统计学意义。这些探索性发现表明，社会压力因素可能是国家层面偏头痛患病率和/或严重程度可改变因素的潜在候选因素。
