胰岛素抵抗对糖尿病患者运动中心血管控制的影响。
The Impact of Insulin Resistance on Cardiovascular Control During Exercise in Diabetes.
机构信息
Department of Applied Clinical Research.
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
出版信息
Exerc Sport Sci Rev. 2021 Jul 1;49(3):157-167. doi: 10.1249/JES.0000000000000259.
Abstract
Patients with diabetes display heightened blood pressure response to exercise, but the underlying mechanism remains to be elucidated. There is no direct evidence that insulin resistance (hyperinsulinemia or hyperglycemia) impacts neural cardiovascular control during exercise. We propose a novel paradigm in which hyperinsulinemia or hyperglycemia significantly influences neural regulatory pathways controlling the circulation during exercise in diabetes.
摘要
糖尿病患者在运动时会出现血压升高的反应，但其中的机制仍有待阐明。目前没有直接的证据表明胰岛素抵抗（高胰岛素血症或高血糖）会影响运动期间的神经心血管控制。我们提出了一个新的假说，即高胰岛素血症或高血糖会显著影响控制糖尿病患者运动期间血液循环的神经调节途径。
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