School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, AUSTRALIA.
Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, BRAZIL.
Med Sci Sports Exerc. 2021 Oct 1;53(10):2076-2085. doi: 10.1249/MSS.0000000000002696.
The aims of this study were to investigate the cross-sectional and prospective associations between accelerometer-measured physical activity and cardiometabolic health in the transition to adulthood.
Data from the 1993 Pelotas (Brazil) Birth Cohort were analyzed (n = 2280). Moderate-to-vigorous intensity physical activity (MVPA) (measured using a triaxial accelerometer) and cardiometabolic health (total fat mass, blood glucose, non-high-density lipoprotein cholesterol, triglycerides, and mean resting blood pressure) were examined at age 18 and 22 yr.
Overall, inverse dose-response associations between MVPA and cardiometabolic health at age 18 and 22 yr were observed in cross-sectional analyses of data from men and women. Prospective analyses showed that, in general, MVPA declined, and cardiometabolic health worsened in this 4-yr period in both men and women. Cardiometabolic health at age 22 yr reflected both MVPA at age 18 yr (β, -0.007; 95% confidence interval [CI], -0.014 to 0.000) and changes in MVPA from 18 to 22 yr (β, -0.030; 95% CI, -0.043 to -0.016) in men, but only changes in MVPA in women (β, -0.035; 95% CI, -0.058 to -0.011). In analyses of change over time, men who improved MVPA by 20 to 30 min·d-1 showed significant improvements in cardiometabolic health over 4 yr. The magnitude of association was slightly stronger for MVPA in 10-min bouts than for MVPA accumulated in bouts of 1 min, especially in women.
Moderate-to-vigorous intensity physical activity is an important predictor of cardiometabolic health in early adulthood. Strategies to prevent declines in MVPA at this life stage are required to prevent deteriorating cardiometabolic health profiles.
本研究旨在探讨青少年向成年过渡期内,通过加速度计测量的身体活动与心血管代谢健康的横断面和前瞻性关联。
本研究分析了 1993 年巴西佩洛塔斯出生队列(n = 2280)的数据。在 18 岁和 22 岁时,使用三轴加速度计测量中高强度体力活动(MVPA)和心血管代谢健康(总脂肪量、血糖、非高密度脂蛋白胆固醇、甘油三酯和平均静息血压)。
在男女的横断面分析中,MVPA 与 18 岁和 22 岁时心血管代谢健康之间呈负相关。前瞻性分析显示,在这 4 年期间,男女的 MVPA 普遍下降,心血管代谢健康状况恶化。22 岁时的心血管代谢健康反映了 18 岁时的 MVPA(β,-0.007;95%置信区间[CI],-0.014 至 0.000)和 18 岁至 22 岁期间 MVPA 的变化(β,-0.030;95%CI,-0.043 至 -0.016)。但仅在女性中,MVPA 的变化与心血管代谢健康有关(β,-0.035;95%CI,-0.058 至 -0.011)。在随时间变化的分析中,MVPA 增加 20 至 30 分钟/天的男性在 4 年内心血管代谢健康有显著改善。10 分钟段的 MVPA 与 1 分钟段的 MVPA 相比,其关联强度稍大,尤其是在女性中。
中高强度体力活动是成年早期心血管代谢健康的重要预测因素。需要制定策略来防止这个生命阶段 MVPA 的下降,以防止心血管代谢健康状况恶化。