Department of Musculoskeletal Disorders and Physical Work Load, National Research Centre for the Working Environment, Copenhagen, DENMARK.
Med Sci Sports Exerc. 2024 Jul 1;56(7):1297-1306. doi: 10.1249/MSS.0000000000003415. Epub 2024 Feb 26.
Physical activity, sedentary behavior, and sleep, that is, 24-h movement behaviors, often change in the transition from work to retirement, which may affect cardiometabolic health. This study investigates the longitudinal associations between changes in 24-h movement behaviors and cardiometabolic biomarkers during the retirement transition.
Retiring public sector workers ( n = 212; mean (SD) age, 63.5 (1.1) yr) from the Finnish Retirement and Aging study used a thigh-worn Axivity accelerometer and filled out a diary to obtain data on daily time spent in sedentary behavior (SED), light physical activity (LPA), and moderate-to-vigorous physical activity (MVPA), and sleep before and after retirement (1 yr in-between). Cardiometabolic biomarkers, including LDL-cholesterol, HDL-cholesterol, total/HDL-cholesterol ratio, triglycerides, C-reactive protein, fasting glucose, and insulin, were measured. Associations between changes in 24-h movement behaviors and cardiometabolic biomarkers were analyzed using compositional robust regression and isotemporal substitution analysis.
Increasing LPA in relation to remaining behaviors was associated with an increase in HDL-cholesterol and decrease in total/HDL-cholesterol ratio ( P < 0.05 for both). For instance, reallocation of 30 min from sleep/SED to LPA was associated with an increase in HDL-cholesterol by 0.02 mmol·L -1 . Moreover, increasing MVPA in relation to remaining behaviors was associated with a decrease in triglycerides ( P = 0.02). Reallocation of 30 min from SED/sleep to MVPA was associated with 0.07-0.08 mmol·L -1 decrease in triglycerides. Findings related to LDL-cholesterol, C-reactive protein, fasting glucose, and insulin were less conclusive.
During the transition from work to retirement, increasing physical activity at the expense of passive behaviors was associated with a better lipid profile. Our findings suggest that life transitions like retirement could be utilized more as an optimal time window for promoting physical activity and health.
体力活动、久坐行为和睡眠，即 24 小时的运动行为，在从工作到退休的过渡期间通常会发生变化，这可能会影响心血管代谢健康。本研究调查了退休过渡期间 24 小时运动行为变化与心血管代谢生物标志物之间的纵向关联。
来自芬兰退休和衰老研究的 212 名即将退休的公共部门工作人员（平均（SD）年龄，63.5（1.1）岁）使用大腿佩戴的 Axivity 加速度计并填写日记，以获取退休前后（1 年）每天久坐行为（SED）、低强度体力活动（LPA）和中高强度体力活动（MVPA）和睡眠的时间数据。测量了心血管代谢生物标志物，包括 LDL-胆固醇、HDL-胆固醇、总/HDL-胆固醇比值、甘油三酯、C 反应蛋白、空腹血糖和胰岛素。使用组成稳健回归和等时替代分析来分析 24 小时运动行为变化与心血管代谢生物标志物之间的关联。
与剩余行为相比，增加 LPA 与 HDL-胆固醇增加和总/HDL-胆固醇比值降低相关（两者均 P <0.05）。例如，将 30 分钟的睡眠时间/SED 重新分配给 LPA 与 HDL-胆固醇增加 0.02 mmol·L -1 相关。此外，与剩余行为相比，增加 MVPA 与甘油三酯降低相关（P = 0.02）。将 30 分钟的 SED/睡眠重新分配给 MVPA 与甘油三酯降低 0.07-0.08 mmol·L -1 相关。与 LDL-胆固醇、C 反应蛋白、空腹血糖和胰岛素相关的发现不太明确。
在从工作到退休的过渡期间，以体力活动代替被动行为会导致更好的血脂水平。我们的研究结果表明，像退休这样的生活过渡可以更多地被利用为促进体力活动和健康的最佳时间窗口。
