Ninomiya H, Nakamura T
Department of Laboratory Animal Science, Azabu University, School of Veterinary Medicine, Kanagawa, Japan.
Jikken Dobutsu. 1988 Apr;37(2):153-8. doi: 10.1538/expanim1978.37.2_153.
Vascular changes in the hydronephrotic glomeruli of rats were examined using corrosion casts, India ink injection and histological methods. In severe cases, the diameter of the glomerular capillary conglomerations decreased to 40-90 microns as a result of glomerular atrophy. The capillaries of these glomeruli also had reduced diameters, and were strangulated and torn off to varying degrees. The intact capillary network of the renal medulla was destroyed and the normal alignment of capillaries parallel to the tubules was lost. These morphological characteristics may account in part for the difficulty in glomerular capillary blood circulation.
采用铸型腐蚀法、墨汁灌注法和组织学方法，对大鼠肾积水肾小球的血管变化进行了研究。在严重病例中，由于肾小球萎缩，肾小球毛细血管丛的直径缩小至40 - 90微米。这些肾小球的毛细血管直径也减小，且不同程度地受到挤压和撕裂。肾髓质完整的毛细血管网遭到破坏，与肾小管平行排列的毛细血管正常排列消失。这些形态学特征可能部分解释了肾小球毛细血管血液循环困难的原因。
