Xie Zhao Yun, Bai Hua, Deng Fei Fei
Department of Infection Management,The Third Affiliated Hospital of Guizhou Medical University,Duyun,Guizhou 558000,China.
Department of Neurology,The Third Affiliated Hospital of Guizhou Medical University,Duyun,Guizhou 558000,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2021 Apr 28;43(2):188-192. doi: 10.3881/j.issn.1000-503X.12916.
Objective To verify the relationship between catheter-related urinary tract infection(CAUTI)and stress hyperglycemia during catheter retention in stroke patients. Methods We used nosocomial infection monitoring system to track the status of CAUTI in stroke patients in a hospital.The study cohort was all the patients who received retention catheterization from January 2016 to March 2020.According to the nested case-control design,multivariate logistic regression analysis was performed to explore the relationship between stress hyperglycemia and CAUTI in stroke patients with indwelling catheter. Results A total of 322 cases of CAUTI and 644 cases of non-CAUTI were enrolled in this study.The length of stay in the case group was(20.68 ± 3.73)d,significantly longer than that[(13.00 ± 4.01)d]in the control group(t=29.473,P <0.001).Compared with non-stress hyperglycemia,stress hyperglycemia posed a higher risk of CAUTI in the stroke patients with indwelling catheter(OR=2.020,95% CI=1.447-2.821,P=0.000)and led to the higher incidence of CAUTI in one thousand days(P<0.001). Conclusion Stress hyperglycemia in the stroke patients with indwelling catheter can significantly increase the risk of CAUTI.
目的 验证脑卒中患者留置导尿管期间导管相关尿路感染（CAUTI）与应激性高血糖之间的关系。方法 采用医院感染监测系统追踪某医院脑卒中患者CAUTI的发生情况。研究队列包括2016年1月至2020年3月期间所有接受留置导尿的患者。根据巢式病例对照设计，对留置导尿管的脑卒中患者进行多因素logistic回归分析，以探讨应激性高血糖与CAUTI之间的关系。结果 本研究共纳入322例CAUTI患者和644例非CAUTI患者。病例组的住院时间为（20.68±3.73）天，显著长于对照组[（13.00±4.01）天]（t=29.473，P<0.001）。与非应激性高血糖相比，应激性高血糖使留置导尿管的脑卒中患者发生CAUTI的风险更高（OR=2.020，95%CI=1.447-2.821，P=0.000），且导致每千日CAUTI发病率更高（P<0.001）。结论 留置导尿管的脑卒中患者应激性高血糖可显著增加CAUTI的发生风险。
