Wang Meng Meng, Wang Ying, Chen Zhao Jing, Xu Chang Qing, Wang Yi, Yang Jun, Zhang Long, Li Hong Juan
School of Public Health,Hangzhou Normal University Division of Health Sciences,Hangzhou 311121,China.
Center for Uterine Cancer Diagnosis and Therapy Research of Zhejiang Province,Women's Hospital,School of Medicine,Zhejiang University,Hangzhou 310006,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2021 Apr 28;43(2):253-258. doi: 10.3881/j.issn.1000-503X.13177.
Gestational diabetes mellitus(GDM)can cause blood glucose disorders in pregnant women and result in adverse maternal-neonatal outcomes.Vitamin D(VD)can improve glucose tolerance and insulin sensitivity,and thus theoretically,VD supplementation during pregnancy could improve glycemic control as well as maternal-neonatal outcomes in GDM patients.Although studies have shown that VD deficiency is associated with poor maternal-neonatal outcomes in GDM patients,no solid conclusion has been drawn with regard to the effects of VD supplementation on these patients.Therefore,here we summarized the research progress of the effects of VD supplementation on glycemic control and adverse maternal-neonatal outcomes in GDM patients,in an effort to guide the clinical VD supplementation during pregnancy.
妊娠期糖尿病（GDM）可导致孕妇血糖紊乱，并导致不良的母婴结局。维生素D（VD）可改善糖耐量和胰岛素敏感性，因此从理论上讲，孕期补充VD可改善GDM患者的血糖控制以及母婴结局。尽管研究表明，VD缺乏与GDM患者不良的母婴结局相关，但关于补充VD对这些患者的影响尚未得出确凿结论。因此，我们在此总结了补充VD对GDM患者血糖控制及不良母婴结局影响的研究进展，以期指导孕期临床VD补充。
