高剂量地昔帕明、血浆药物水平与临床反应。
High dose desipramine, plasma drug levels and clinical response.
作者信息
Amsterdam J, Brunswick D J, Mendels J
出版信息
J Clin Psychiatry. 1979 Mar;40(3):141-3.
PMID:33968
Abstract
The concentration of tricyclic antidepressants in plasma may be a more important factor than the oral dose in determining whether or not a patient will respond to treatment. Knowledge of the drug dose-response curve and its levels in blood may enable the physician to convert a patient from a "nonresponder" into a "responder."
摘要
在确定患者是否会对治疗产生反应时，血浆中三环类抗抑郁药的浓度可能比口服剂量更重要。了解药物剂量反应曲线及其血液中的水平，可能使医生将患者从“无反应者”转变为“有反应者”。
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