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在一家大型城市安全网医疗中心,对新冠病毒检测呈阳性的患者进行手术后与新冠病毒2型相关的结果。

SARS-CoV-2-related outcomes after surgical procedures on SARS-CoV-2-positive patients in a large, urban, safety net medical center.

作者信息

Sargent Rachel E, Sener Stephen F, Amaya Rodolfo, Vazquez Elizabeth, Bowdish Michael E, Spellberg Brad

机构信息

Los Angeles County + University of Southern California (LAC + USC) Medical Center, Los Angeles, CA.

Department of Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA.

出版信息

Surg Open Sci. 2021 Jul;5:10-13. doi: 10.1016/j.sopen.2021.04.001. Epub 2021 May 3.

Abstract

BACKGROUND

Beginning on March 16, 2020, nonurgent scheduled operations at a large, urban, safety net medical center were canceled. The purpose of this study was to determine complications associated with severe acute respiratory syndrome coronavirus 2 infection for all operations done from March 16 to June 30, 2020.

STUDY DESIGN

This study was a single-institution, retrospective observational analysis of data for all surgical procedures and all severe acute respiratory syndrome coronavirus 2 tests done in the medical center from March 16 to June 30, 2020. The charts of all severe acute respiratory syndrome coronavirus 2-positive patients who had a surgical procedure during the study time period were retrospectively reviewed to assess the outcomes.

RESULTS

Of 2,208 operations during that time, 29 (1.3%) patients were severe acute respiratory syndrome coronavirus 2-positive and were asymptomatic at the time of their operations. Twenty-four (82.7%) of the 29 required urgent or emergent procedures. The median time between availability of test results and operations for these patients was 0.63 + 1.94 days. With median follow-up of 89 days, none of the 29 patients died from severe acute respiratory syndrome coronavirus 2-related causes, and none developed clinically evident thromboembolism or required reintubation secondary to severe acute respiratory syndrome coronavirus 2-related pneumonia.

CONCLUSION

By operating on carefully screened, asymptomatic severe acute respiratory syndrome coronavirus 2-positive patients, it was possible to eliminate major complications and mortality due to severe acute respiratory syndrome coronavirus 2 infection.

摘要

背景

从2020年3月16日起,一家大型城市安全网医疗中心取消了非紧急的预定手术。本研究的目的是确定2020年3月16日至6月30日期间所有手术中与严重急性呼吸综合征冠状病毒2感染相关的并发症。

研究设计

本研究是对该医疗中心2020年3月16日至6月30日期间所有外科手术及所有严重急性呼吸综合征冠状病毒2检测数据进行的单机构回顾性观察分析。对研究期间接受外科手术的所有严重急性呼吸综合征冠状病毒2阳性患者的病历进行回顾性审查,以评估结果。

结果

在此期间的2208例手术中,29例(1.3%)患者严重急性呼吸综合征冠状病毒2呈阳性,且手术时无症状。29例患者中有24例(82.7%)需要紧急或急诊手术。这些患者检测结果可用至手术的中位时间为0.63±1.94天。中位随访89天,29例患者中无1例死于严重急性呼吸综合征冠状病毒2相关原因,也无1例发生临床明显的血栓栓塞或因严重急性呼吸综合征冠状病毒2相关肺炎而需要再次插管。

结论

通过对仔细筛查的无症状严重急性呼吸综合征冠状病毒2阳性患者进行手术,可以消除严重急性呼吸综合征冠状病毒2感染导致的主要并发症和死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d679/8324461/df45f5cd0c40/gr1.jpg

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