García Y, Callejas J, Hernández P
Instituto de Hematología e Immunología, Habana, Cuba.
Haematologia (Budap). 1988;21(1):41-6.
Periodical follow-up evaluations at intervals from 3 to 6 months of haematocrit, blood volume and ferrokinetic, during a 2.5 year period were performed in 18 polycythaemia vera (PV) patients to find the most characteristic parameters for the determination of the erythropoietic system functional activity. Our results suggest that in PV it is advisable to carry out further determination of red cell volume to determine exactly the degree of erythrocytosis. We found that plasma iron turnover (PIT) followed by 59Fe T1/2 are the first parameters to return to normal and the first to alter after a prolonged period of a normal ferrokinetic status. We suggest these may be used as the most reliable indicators for the haematological control of PV.
在2.5年的时间里，对18例真性红细胞增多症（PV）患者每隔3至6个月进行一次血细胞比容、血容量和铁动力学的定期随访评估，以寻找用于确定红细胞生成系统功能活性的最具特征性的参数。我们的结果表明，对于PV患者，建议进一步测定红细胞体积以准确确定红细胞增多的程度。我们发现，血浆铁周转率（PIT）以及随后的59Fe T1/2是在铁动力学状态长期正常后最先恢复正常和最先发生改变的参数。我们认为这些参数可作为PV血液学控制的最可靠指标。
