Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Knowledge City, Sector 81, S. A. S. Nagar, Manauli PO, Punjab, 140306, India.
Chem Rec. 2021 Dec;21(12):3470-3482. doi: 10.1002/tcr.202100095. Epub 2021 May 10.
The development of new synthetic protocols to access diverse molecular scaffolds from readily available starting compounds is of significance in both academia and industry. Towards this, the catalysis by transition metals has been employed as a powerful tool to access molecules with broad structural and functional diversity. An overview of the recent literature manifested the tremendous potential of transition metal-catalyzed processes in advancing organic synthesis in a new direction. This account compiles new conceptual advancements in the palladium-catalyzed Alder-ene type cycloisomerization reactions, C-H functionalizations, and one-pot multicatalytic processes, which have become essential tools to access new classes of molecules.
开发新的合成方案，从易得的起始原料中获取不同的分子骨架，这在学术界和工业界都具有重要意义。为此，过渡金属催化已被用作一种强大的工具，用于获得具有广泛结构和功能多样性的分子。近期文献综述表明，过渡金属催化过程在推动有机合成向新方向发展方面具有巨大潜力。本综述总结了钯催化的 Alder-ene 型环异构化反应、C-H 官能化和一锅多催化过程中的新概念进展，这些已成为获取新类分子的重要工具。
