Jiang Hong-Ying, Li Qing, Yu Xin, Zhang Chen-Xi, Li Yi, Niu Guang-Yu, Tong Zhao-Hui, Xi Jia-Ning, Zhao Zhanqi
Department of Respiratory and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China.
Department of Respiratory Rehabilitation Center, Beijing Rehabilitation Hospital of Capital Medical University, Beijing, People's Republic of China.
Physiol Meas. 2021 Oct 29;42(10). doi: 10.1088/1361-6579/abffbf.
Due to radiation exposure, not all patients with pneumonia receive chest x-rays or CT measurements to confirm treatment effectiveness. The aim of this study was to examine the ability to use electrical impedance tomography (EIT) to evaluate the treatment effectiveness in such patient group.A total of 35 consecutive patients with non-severe pneumonia were included in this prospective study. The patients received standard treatment according to our internal protocol. EIT measurements were performed in supine position before the treatment started and on day 6 of the treatment period. The EIT-based global inhomogeneity () index and center of ventilation () index were calculated. The clinical pulmonary infection score (CPIS) was obtained at both time points.Clinically significant improvements inandwere found in the patient group (Δ: -34% ± 17% and Δ: -10% ± 11%;<0.001). Although the CPIS was also significantly improved (Δ-0.70 ± 0.17,<0.001), no correlations were demonstrated when compared to Δor ΔEIT demonstrated individual improvement of ventilation heterogeneity after standard treatment in non-severe pneumonia, and provided different information compared to CPIS. EIT has the potential to become a routine non-invasive, non-radiative tool to assess pneumonia treatment effectiveness.
由于辐射暴露，并非所有肺炎患者都接受胸部X光或CT测量以确认治疗效果。本研究的目的是检验使用电阻抗断层扫描（EIT）评估此类患者群体治疗效果的能力。
本前瞻性研究共纳入了35例连续的非重症肺炎患者。患者根据我们的内部方案接受标准治疗。在治疗开始前和治疗期第6天，患者取仰卧位进行EIT测量。计算基于EIT的全局不均匀性（）指数和通气中心（）指数。在两个时间点均获得临床肺部感染评分（CPIS）。
患者组的和有临床显著改善（Δ：-34% ± 17%和Δ：-10% ± 11%；<0.001）。虽然CPIS也有显著改善（Δ -0.70 ± 0.17，<0.001），但与Δ或Δ相比未显示出相关性。
EIT显示非重症肺炎患者在标准治疗后通气异质性有个体改善，并且与CPIS相比提供了不同的信息。EIT有潜力成为评估肺炎治疗效果的常规非侵入性、无辐射工具。
