Suppr超能文献

评估和可视化动脉瘤囊和颈部的血流动力学负荷:泡沫插入的效果。

Assessment and visualization of hemodynamic loading in aneurysm sac and neck: Effect of foam insertion.

机构信息

Department of Mechanical Engineering, Indian Institute of Technology Kanpur, Kanpur, UP, India.

出版信息

Proc Inst Mech Eng H. 2021 Aug;235(8):927-939. doi: 10.1177/09544119211015569. Epub 2021 May 10.

Abstract

Shape memory polymer (SMP) foam is often proposed as the future alternative of coils in aneurysm treatment devices. Present work numerically investigates the unsteady, three-dimensional simulation of blood flow in a cerebral aneurysm filled with SMP foam. Simulations are conducted on patient-specific geometries with realistic blood velocity waveform imposed at the inlet while SMP foam is treated as a porous medium. The present study introduces a "loading risk map" that helps to visualize the hemodynamic effect of foam insertion on the aneurysm sac and neck. The loading risk maps suggest that while the SMP foam subdues the flow and wall shear pulsations in the aneurysm sac, the pressure distribution is minimally affected. The maps suggest that while the downstream lip is the most risk-prone site for both geometries, downstream vascular anatomy significantly influences foam efficiency in reducing pressure and wall shear stress loading.

摘要

形状记忆聚合物(SMP)泡沫常被提议作为动脉瘤治疗装置中线圈的未来替代品。本工作通过数值方法研究了充满 SMP 泡沫的脑动脉瘤中血液流动的非定常、三维模拟。在入口处施加真实血流速度波形的情况下,对特定于患者的几何形状进行模拟,同时将 SMP 泡沫视为多孔介质。本研究引入了“加载风险图”,有助于可视化泡沫插入对动脉瘤囊和颈部的血流动力学影响。加载风险图表明,虽然 SMP 泡沫抑制了动脉瘤囊中血流和壁切变的脉动,但压力分布受影响很小。这些图谱表明,虽然对于两种几何形状,下游唇都是最易受影响的部位,但下游血管解剖结构显著影响泡沫降低压力和壁切应力负荷的效率。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验