Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Int J Eat Disord. 2021 Jun;54(6):1055-1062. doi: 10.1002/eat.23535. Epub 2021 May 11.
Gastrointestinal (GI) concerns are often presumed to complicate nutritional rehabilitation for restrictive eating disorders, yet their relationship to weight restoration outcomes is unclear. This retrospective chart review examined GI history and weight-related discharge outcomes in primarily adult, underweight inpatients with anorexia nervosa (AN, N = 107) or avoidant/restrictive food intake disorder (ARFID, N = 22) treated in a meal-based, behavioral eating disorder program.
Lifetime GI symptomatology, diagnoses, diagnostic tests, and procedures were abstracted from medical records. Generalized linear models examined associations of GI diagnoses, tests, and procedures with discharge BMI and rate of weight gain.
Ninety-nine percent of patients reported GI symptomatology and 83% had one or more GI diagnoses; with constipation and GERD most common. GI diagnoses (p <.01) and testing (p <.001) were more common in ARFID than AN. Average inpatient weight gain (1.59 kg/week), and discharge BMI (18.5 kg/m ), did not differ by group. Slower weight gain in patients with (1.3 kg/week), versus without (1.7 kg/week), history of tube feeding (p = .02), accounted for a main effect of GI procedures on inpatient rate of gain (p = .01).
Despite ubiquitous GI symptomatology, meal-based weight restoration achieved average weekly weight gain above recommended APA guidelines for hospitalized patients with an eating disorder. History of tube feeding was associated with slower mean weight gain, which remained, however, within recommended APA guidelines.
胃肠道 (GI) 问题通常被认为会使限制型进食障碍的营养康复复杂化,但它们与体重恢复结果的关系尚不清楚。本回顾性图表研究检查了主要为成年人、体重不足的神经性厌食症 (AN,N=107) 或回避/限制型食物摄入障碍 (ARFID,N=22) 住院患者的 GI 病史和与体重相关的出院结果,这些患者在以膳食为基础的行为饮食障碍计划中接受治疗。
从病历中提取了终生 GI 症状、诊断、诊断性检查和程序。广义线性模型检查了 GI 诊断、检查和程序与出院 BMI 和体重增加率的关联。
99%的患者报告有 GI 症状,83%的患者有一个或多个 GI 诊断;便秘和 GERD 最常见。ARFID 比 AN 的 GI 诊断 (p<.01) 和检查 (p<.001) 更常见。平均住院体重增加 (1.59 公斤/周) 和出院 BMI (18.5 公斤/米 ) 不因组而异。有 (1.3 公斤/周) 和没有 (1.7 公斤/周) 管饲喂养史的患者的体重增加较慢 (p=.02),这解释了 GI 程序对住院期间增重率的主要影响 (p=.01)。
尽管存在普遍的胃肠道症状,但基于膳食的体重恢复达到了 APA 住院患者进食障碍推荐的每周增重平均值。管饲喂养史与平均体重增加较慢相关,但仍在 APA 推荐范围内。