Department of Pediatrics, Division of Hematology/Oncology.
Division of Infectious Diseases.
J Pediatr Hematol Oncol. 2022 Mar 1;44(2):e428-e430. doi: 10.1097/MPH.0000000000002155.
Sickle beta+thalassemia is considered to be a mild form of sickle cell disease. However, some patients with mild disease can present with osteonecrosis. Here, we present a rare 3-year-old male who presented with acute pain, a baseline hemoglobin of 13 g/dL, who acutely developed multifocal osteonecrosis, and improved with partial exchange transfusion and hydroxyurea therapy.
镰状细胞β+地中海贫血被认为是一种轻度镰状细胞病。然而，一些轻度疾病的患者可能会出现骨坏死。在这里，我们介绍了一位罕见的 3 岁男性患者，他表现为急性疼痛，基线血红蛋白为 13g/dL，突然出现多处骨坏死，并通过部分换血和羟基脲治疗得到改善。
